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Gene: KLF5 (Kruppel like factor 5) Homo sapiens
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Symbol: KLF5
Name: Kruppel like factor 5
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in cell-cell signaling via exosome and positive regulation of pri-miRNA transcription by RNA polymerase II. Localizes to the Golgi apparatus and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: (intestinal Kruppel-like factor; basic transcription element binding protein 2; basic transcription element-binding protein 2; BTE-binding protein 2; BTEB2; CKLF; colon krueppel-like factor; colon kruppel-like factor; GC box binding protein 2; GC-box-binding protein 2; IKLF; intestinal-enriched krueppel-like factor; intestinal-enriched kruppel-like factor; Klf5C isoform; Krueppel-like factor 5; Kruppel-like factor 5 (intestinal); transcription factor BTEB2
Orthologs:
Mus musculus (house mouse) : Klf5 (Kruppel-like factor 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Klf5 (Kruppel-like factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf5 (Kruppel like factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF5 (Kruppel like factor 5)
Canis lupus familiaris (dog) : KLF5 (Kruppel like factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf5 (Kruppel like factor 5)
Sus scrofa (pig) : KLF5 (Kruppel like factor 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381373,054,976 - 73,077,542 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371373,629,114 - 73,651,676 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361372,531,143 - 72,549,677 (+)NCBINCBI36hg18NCBI36
Build 341372,531,142 - 72,549,677NCBI
Celera1354,531,627 - 54,550,162 (+)NCBI
Cytogenetic Map13q22.1NCBI
HuRef1354,330,388 - 54,348,922 (+)NCBIHuRef
CHM1_11373,596,724 - 73,619,293 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KLF5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345927
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.