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Gene: DAXX (death domain associated protein) Homo sapiens
Symbol: DAXX
Name: death domain associated protein
Description: Exhibits several functions, including androgen receptor binding activity; enzyme binding activity; and transcription coregulator activity. Involved in several processes, including cellular response to metal ion; chromatin organization; and regulation of protein modification process. Localizes to PML body and chromosome, centromeric region. Implicated in ovary epithelial cancer. Biomarker of carcinoma (multiple); endocrine gland cancer (multiple); leukemia; and prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BING2; CENP-C binding protein; DAP6; death domain-associated protein 6; death-associated protein 6; EAP1; ETS1-associated protein 1; fas death domain-associated protein; Fas-binding protein; hDaxx; MGC126245; MGC126246; SMIM40
Mus musculus (house mouse) : Daxx (Fas death domain-associated protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Daxx (death-domain associated protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Daxx (death domain associated protein)
Pan paniscus (bonobo/pygmy chimpanzee) : DAXX (death domain associated protein)
Canis lupus familiaris (dog) : DAXX (death domain associated protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Daxx (death domain associated protein)
Sus scrofa (pig) : DAXX (death domain associated protein)
Chlorocebus sabaeus (African green monkey) : DAXX (death domain associated protein)
Heterocephalus glaber (naked mole-rat) : Daxx (death domain associated protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl633,318,558 - 33,323,016 (-)EnsemblGRCh38hg38GRCh38
GRCh38633,318,558 - 33,323,016 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37633,286,335 - 33,290,793 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,394,367 - 33,398,682 (-)NCBINCBI36hg18NCBI36
Build 34633,394,380 - 33,398,682NCBI
Celera634,840,701 - 34,845,159 (-)NCBI
Cytogenetic Map6p21.32NCBI
HuRef633,027,906 - 33,032,806 (-)NCBIHuRef
CHM1_1633,288,251 - 33,292,710 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DAXX
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345950
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.