Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MC3R (melanocortin 3 receptor) Homo sapiens
Symbol: MC3R
Name: melanocortin 3 receptor
Description: Exhibits melanocyte-stimulating hormone receptor activity and neuropeptide binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to localize to the integral component of plasma membrane. Implicated in obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BMIQ9; MC3; MC3-R; melanocortin receptor 3; OB20; Obesity quantitative trait locus; OQTL
Mus musculus (house mouse) : Mc3r (melanocortin 3 receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mc3r (melanocortin 3 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mc3r (melanocortin 3 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : MC3R (melanocortin 3 receptor)
Canis lupus familiaris (dog) : MC3R (melanocortin 3 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mc3r (melanocortin 3 receptor)
Sus scrofa (pig) : MC3R (melanocortin 3 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382056,248,732 - 56,249,815 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372054,823,788 - 54,824,871 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362054,257,196 - 54,258,278 (+)NCBINCBI36hg18NCBI36
Build 342054,257,195 - 54,258,278NCBI
Celera2051,563,099 - 51,564,182 (+)NCBI
Cytogenetic Map20q13.2NCBI
HuRef2051,605,969 - 51,607,052 (+)NCBIHuRef
CHM1_12054,724,847 - 54,725,930 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MC3R
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345990
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.