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Gene: SGSH (N-sulfoglucosamine sulfohydrolase) Homo sapiens
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Symbol: SGSH
Name: N-sulfoglucosamine sulfohydrolase
Description: Exhibits N-sulfoglucosamine sulfohydrolase activity. Involved in glycosaminoglycan catabolic process and heparan sulfate proteoglycan catabolic process. Localizes to the lysosome. Implicated in mucopolysaccharidosis III.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: heparan sulfate sulfatase; HSS; MPS3A; mucopolysaccharidosis type IIIA; N-sulphoglucosamine sulphohydrolase; SFMD; sulfoglucosamine sulfamidase; sulphamidase
Orthologs:
Mus musculus (house mouse) : Sgsh (N-sulfoglucosamine sulfohydrolase (sulfamidase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Sgsh (N-sulfoglucosamine sulfohydrolase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sgsh (N-sulfoglucosamine sulfohydrolase)
Pan paniscus (bonobo/pygmy chimpanzee) : SGSH (N-sulfoglucosamine sulfohydrolase)
Canis lupus familiaris (dog) : SGSH (N-sulfoglucosamine sulfohydrolase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sgsh (N-sulfoglucosamine sulfohydrolase)
Sus scrofa (pig) : SGSH (N-sulfoglucosamine sulfohydrolase)
Chlorocebus sabaeus (green monkey) : SGSH (N-sulfoglucosamine sulfohydrolase)
Heterocephalus glaber (naked mole-rat) : Sgsh (N-sulfoglucosamine sulfohydrolase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1780,206,716 - 80,220,923 (-)Ensembl
GRCh381780,200,668 - 80,220,333 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371778,180,515 - 78,194,199 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361775,797,685 - 75,808,719 (-)NCBINCBI36hg18NCBI36
Build 341775,797,684 - 75,808,719NCBI
Celera1774,812,270 - 74,823,389 (-)NCBI
Cytogenetic Map17q25.3NCBI
HuRef1773,623,348 - 73,634,467 (-)NCBIHuRef
CHM1_11778,269,258 - 78,280,378 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
 
More on SGSH
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1345995
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.