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Gene: ATP6AP2 (ATPase H+ transporting accessory protein 2) Homo sapiens
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Symbol: ATP6AP2
Name: ATPase H+ transporting accessory protein 2
Description: This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APT6M8-9; ATP6IP2; ATP6M8-9; ATPase H(+)-transporting lysosomal-interacting protein 2; ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9; ATPase, H+ transporting, lysosomal accessory protein 2; ATPase, H+ transporting, lysosomal interacting protein 2; ELDF10; embryonic liver differentiation factor 10; ER-localized type I transmembrane adaptor; HT028; M8-9; MGC99577; MRXE; MRXSH; MSTP009; N14F; prorenin receptor; PRR; renin receptor; renin/prorenin receptor; RENR; V-ATPase M8.9 subunit; vacuolar ATP synthase membrane sector-associated protein M8-9; vacuolar proton ATP synthase membrane sector associated protein M8-9; XMRE; XPDS
Orthologs:
Mus musculus (house mouse) : Atp6ap2 (ATPase, H+ transporting, lysosomal accessory protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atp6ap2 (ATPase H+ transporting accessory protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp6ap2 (ATPase H+ transporting accessory protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP6AP2 (ATPase H+ transporting accessory protein 2)
Canis lupus familiaris (dog) : ATP6AP2 (ATPase H+ transporting accessory protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp6ap2 (ATPase H+ transporting accessory protein 2)
Sus scrofa (pig) : ATP6AP2 (ATPase H+ transporting accessory protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X40,580,964 - 40,606,637 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X40,440,141 - 40,465,889 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X40,325,160 - 40,350,833 (+)NCBINCBI36hg18NCBI36
Build 34X40,196,446 - 40,222,125NCBI
CeleraX44,580,390 - 44,606,072 (+)NCBI
Cytogenetic MapXp11.4NCBI
HuRefX38,171,318 - 38,196,989 (+)NCBIHuRef
CHM1_1X40,472,702 - 40,498,380 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Protein Structures
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ATP6AP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346001
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.