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Gene: SOCS5 (suppressor of cytokine signaling 5) Homo sapiens
Symbol: SOCS5
Name: suppressor of cytokine signaling 5
Description: Exhibits receptor tyrosine kinase binding activity. Involved in negative regulation of epidermal growth factor-activated receptor activity and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to localize to phosphatidylinositol 3-kinase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CIS-6; CIS6; Cish5; CISH6; cytokine-inducible SH2 protein 6; cytokine-inducible SH2-containing protein 5; KIAA0671; SOCS-5
Mus musculus (house mouse) : Socs5 (suppressor of cytokine signaling 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Socs5 (suppressor of cytokine signaling 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Socs5 (suppressor of cytokine signaling 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SOCS5 (suppressor of cytokine signaling 5)
Canis lupus familiaris (dog) : SOCS5 (suppressor of cytokine signaling 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Socs5 (suppressor of cytokine signaling 5)
Sus scrofa (pig) : SOCS5 (suppressor of cytokine signaling 5)
Chlorocebus sabaeus (African green monkey) : SOCS5 (suppressor of cytokine signaling 5)
Heterocephalus glaber (naked mole-rat) : Socs5 (suppressor of cytokine signaling 5)
more info ...
Related Pseudogenes: SOCS5P1   SOCS5P2   SOCS5P3   SOCS5P4   SOCS5P5  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl246,698,952 - 46,780,245 (+)EnsemblGRCh38hg38GRCh38
GRCh38246,698,960 - 46,763,129 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37246,926,099 - 46,989,927 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36246,779,603 - 46,843,431 (+)NCBINCBI36hg18NCBI36
Build 34246,837,999 - 46,901,578NCBI
Celera246,764,784 - 46,828,608 (+)NCBI
Cytogenetic Map2p21NCBI
HuRef246,663,409 - 46,727,912 (+)NCBIHuRef
CHM1_1246,856,418 - 46,920,225 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SOCS5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346055
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.