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Gene: SERPINB3 (serpin family B member 3) Homo sapiens
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Symbol: SERPINB3
Name: serpin family B member 3
CRRD ID: 1346118
Description: Exhibits cysteine-type endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Involved in several processes, including autocrine signaling; paracrine signaling; and regulation of cellular protein metabolic process. Localizes to cytoplasmic vesicle; extracellular exosome; and nucleus; PARTICIPATES IN Entamoebiasis pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-phenylprop-2-enal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HsT1196; SCC; SCCA-1; SCCA-PD; SCCA1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serpin B3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; squamous cell carcinoma antigen 1; SSCA1; T4-A
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1863,655,197 - 63,661,893 (-)EnsemblGRCh38hg38GRCh38
GRCh381863,655,197 - 63,661,893 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371861,322,431 - 61,329,259 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361859,473,411 - 59,480,094 (-)NCBINCBI36hg18NCBI36
Build 341859,473,410 - 59,480,094NCBI
Celera1858,042,926 - 58,049,692 (-)NCBI
Cytogenetic Map18q21.33NCBI
HuRef1858,022,262 - 58,029,029 (-)NCBIHuRef
CHM1_11861,318,618 - 61,325,385 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SERPINB3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346118
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.