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Gene: SERPINA5 (serpin family A member 5) Homo sapiens
Symbol: SERPINA5
Name: serpin family A member 5
Description: Exhibits anion binding activity; enzyme binding activity; and serine-type endopeptidase inhibitor activity. Involved in negative regulation of hydrolase activity. Localizes to several cellular components, including the protein C inhibitor-KLK3 complex; protein C inhibitor-PLAT complex; and secretory granule. Colocalizes with the collagen-containing extracellular matrix.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acrosomal serine protease inhibitor; PAI-3; PAI3; PCI; PCI-B; PLANH3; plasma serine protease inhibitor; plasminogen activator inhibitor 3; plasminogen activator inhibitor III; plasminogen activator inhibitor-3; PROCI; protein C inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5; serpin A5; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
Mus musculus (house mouse) : Serpina5 (serine (or cysteine) peptidase inhibitor, clade A, member 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Serpina5 (serpin family A member 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpina5 (serpin family A member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINA5 (serpin family A member 5)
Canis lupus familiaris (dog) : LOC480424 (plasma serine protease inhibitor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpina5 (serpin family A member 5)
Sus scrofa (pig) : SERPINA5 (serpin family A member 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1494,561,442 - 94,593,118 (+)Ensembl
GRCh381494,581,426 - 94,593,118 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371495,047,706 - 95,059,457 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361494,117,564 - 94,129,205 (+)NCBINCBI36hg18NCBI36
Build 341494,117,563 - 94,129,204NCBI
Celera1475,103,903 - 75,115,619 (+)NCBI
Cytogenetic Map14q32.13NCBI
HuRef1475,228,133 - 75,239,873 (+)NCBIHuRef
CHM1_11494,985,498 - 94,997,214 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SERPINA5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346137
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.