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Gene: QARS1 (glutaminyl-tRNA synthetase 1) Homo sapiens
Symbol: QARS1
Name: glutaminyl-tRNA synthetase 1
CRRD ID: 1346181
Description: Exhibits glutamine-tRNA ligase activity; protein kinase binding activity; and protein kinase inhibitor activity. Involved in several processes, including glutaminyl-tRNA aminoacylation; negative regulation of apoptotic signaling pathway; and negative regulation of protein phosphorylation. Localizes to aminoacyl-tRNA synthetase multienzyme complex and cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GLNRS; glutamine tRNA ligase; glutamine--tRNA ligase; glutamine-tRNA synthetase; glutaminyl-tRNA synthetase; MSCCA; PRO2195; QARS
Mus musculus (house mouse) : Qars (glutaminyl-tRNA synthetase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Qars1 (glutaminyl-tRNA synthetase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Qars1 (glutaminyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : QARS1 (glutaminyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : QARS1 (glutaminyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Qars1 (glutaminyl-tRNA synthetase 1)
Sus scrofa (pig) : QARS1 (glutaminyl-tRNA synthetase 1)
Chlorocebus sabaeus (African green monkey) : QARS1 (glutaminyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Qars1 (glutaminyl-tRNA synthetase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl349,095,932 - 49,105,130 (-)EnsemblGRCh38hg38GRCh38
GRCh38349,095,932 - 49,104,758 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,133,365 - 49,142,562 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,108,369 - 49,117,175 (-)NCBINCBI36hg18NCBI36
Build 34349,108,369 - 49,117,175NCBI
Celera349,090,328 - 49,099,123 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,191,896 - 49,201,100 (-)NCBIHuRef
CHM1_1349,086,160 - 49,095,309 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on QARS1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346181
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.