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Gene: POU4F2 (POU class 4 homeobox 2) Homo sapiens
Symbol: POU4F2
Name: POU class 4 homeobox 2
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in MAPK cascade; intracellular estrogen receptor signaling pathway; and regulation of transcription by RNA polymerase II. Localizes to the nuclear speck and transcription factor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: brain-3B; brain-specific homeobox/POU domain protein 3B; Brn-3b; BRN3.2; BRN3B; Brn3b POU domain transcription factor; POU domain class 4 transcription factor 2; POU domain protein; POU domain, class 4, transcription factor 2
Mus musculus (house mouse) : Pou4f2 (POU domain, class 4, transcription factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pou4f2 (POU class 4 homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pou4f2 (POU class 4 homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : POU4F2 (POU class 4 homeobox 2)
Canis lupus familiaris (dog) : POU4F2 (POU class 4 homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou4f2 (POU class 4 homeobox 2)
Sus scrofa (pig) : POU4F2 (POU class 4 homeobox 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh384146,638,893 - 146,642,474 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374147,560,045 - 147,563,623 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364147,779,495 - 147,783,073 (+)NCBINCBI36hg18NCBI36
Build 344147,917,692 - 147,921,228NCBI
Celera4144,880,585 - 144,884,163 (+)NCBI
Cytogenetic Map4q31.22NCBI
HuRef4143,287,267 - 143,290,856 (+)NCBIHuRef
CHM1_14147,537,342 - 147,540,923 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on POU4F2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346191
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.