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Gene: POU4F2 (POU class 4 homeobox 2) Homo sapiens
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Symbol: POU4F2
Name: POU class 4 homeobox 2
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in MAPK cascade; intracellular estrogen receptor signaling pathway; and regulation of transcription by RNA polymerase II. Localizes to the nuclear speck and transcription factor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: brain-3B; brain-specific homeobox/POU domain protein 3B; Brn-3b; BRN3.2; BRN3B; Brn3b POU domain transcription factor; POU domain class 4 transcription factor 2; POU domain protein; POU domain, class 4, transcription factor 2
Orthologs:
Mus musculus (house mouse) : Pou4f2 (POU domain, class 4, transcription factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pou4f2 (POU class 4 homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pou4f2 (POU class 4 homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : POU4F2 (POU class 4 homeobox 2)
Canis lupus familiaris (dog) : POU4F2 (POU class 4 homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou4f2 (POU class 4 homeobox 2)
Sus scrofa (pig) : POU4F2 (POU class 4 homeobox 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384146,638,893 - 146,642,474 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374147,560,045 - 147,563,623 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364147,779,495 - 147,783,073 (+)NCBINCBI36hg18NCBI36
Build 344147,917,692 - 147,921,228NCBI
Celera4144,880,585 - 144,884,163 (+)NCBI
Cytogenetic Map4q31.22NCBI
HuRef4143,287,267 - 143,290,856 (+)NCBIHuRef
CHM1_14147,537,342 - 147,540,923 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on POU4F2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346191
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.