Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PNPLA4 (patatin like phospholipase domain containing 4) Homo sapiens
Symbol: PNPLA4
Name: patatin like phospholipase domain containing 4
Description: This gene encodes a member of the patatin-like family of phospholipases. The encoded enzyme has both triacylglycerol lipase and transacylase activities and may be involved in adipocyte triglyceride homeostasis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome Y. [provided by RefSeq, Feb 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: calcium independent phospholipases A2 eta; DXS1283E; GS2; IPLA2 eta; IPLA2-ETA; iPLA2eta; patatin-like phospholipase domain containing 4; patatin-like phospholipase domain-containing protein 4
Rattus norvegicus (Norway rat) : Pnpla4 (patatin like phospholipase domain containing 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pnpla4 (patatin like phospholipase domain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PNPLA4 (patatin like phospholipase domain containing 4)
Canis lupus familiaris (dog) : PNPLA4 (patatin like phospholipase domain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pnpla4 (patatin like phospholipase domain containing 4)
Sus scrofa (pig) : PNPLA4 (patatin like phospholipase domain containing 4)
more info ...
Related Pseudogenes: PNPLA4P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X7,898,247 - 7,928,587 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X7,866,804 - 7,895,780 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X7,826,804 - 7,855,443 (-)NCBINCBI36hg18NCBI36
Build 34X7,676,539 - 7,705,179NCBI
CeleraX12,042,080 - 12,071,056 (-)NCBI
Cytogenetic MapXp22.31NCBI
HuRefX5,673,993 - 5,702,740 (-)NCBIHuRef
CHM1_1X7,847,349 - 7,876,320 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PNPLA4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346226
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.