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Gene: FCGR2B (Fc fragment of IgG receptor IIb) Homo sapiens
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Symbol: FCGR2B
Name: Fc fragment of IgG receptor IIb
Description: The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD32; CD32B; CDw32; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma receptor IIb; Fc gamma RIIb; fc-gamma RII-b; Fc-gamma RII-c; fc-gamma-RIIb; Fc-gamma-RIIc; FCG2; FCGR2; FCGR2C; fcRII-b; FcRII-c; IGFR2; igG Fc receptor II-b; IgG Fc receptor II-c; low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c
Orthologs:
Mus musculus (house mouse) : Fcgr2b (Fc receptor, IgG, low affinity IIb)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fcgr2b (Fc fragment of IgG receptor IIb)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fcgr2b (Fc fragment of IgG receptor IIb)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100984838 (low affinity immunoglobulin gamma Fc region receptor II-b)
Canis lupus familiaris (dog) : LOC100856270 (low affinity immunoglobulin gamma Fc region receptor II)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fcgr2b (Fc fragment of IgG receptor IIb)
Sus scrofa (pig) : FCGR2B (Fc fragment of IgG, low affinity IIb, receptor (CD32))
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,647,243 - 161,678,654 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371161,632,905 - 161,648,444 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,899,564 - 159,914,575 (+)NCBINCBI36hg18NCBI36
Build 341158,364,610 - 158,379,618NCBI
Celera1134,746,188 - 134,751,893 (+)NCBI
Cytogenetic Map1q23.3NCBI
HuRef1132,877,468 - 132,892,993 (+)NCBIHuRef
CHM1_11163,054,757 - 163,070,270 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on FCGR2B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346227
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.