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Gene: FAS (Fas cell surface death receptor) Homo sapiens
Symbol: FAS
Name: Fas cell surface death receptor
Description: Exhibits calmodulin binding activity; identical protein binding activity; and kinase binding activity. Involved in several processes, including cell surface receptor signaling pathway; cellular response to hyperoxia; and regulation of cellular protein metabolic process. Localizes to several cellular components, including the CD95 death-inducing signaling complex; membrane raft; and nuclear body. Implicated in several diseases, including autoimmune hypersensitivity disease (multiple); cystic fibrosis; leukemia (multiple); pre-eclampsia (multiple); and urinary system cancer (multiple). Biomarker of several diseases, including autoimmune hypersensitivity disease (multiple); eye disease (multiple); hematologic cancer (multiple); liver disease (multiple); and neurodegenerative disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ALPS1A; APO-1; apo-1 antigen; APO-1 cell surface antigen; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; Delta Fas/APO-1/CD95; Fas (TNF receptor superfamily, member 6); FAS 827dupA; Fas AMA; Fas antigen; FAS receptor variant 9; FAS1; FASLG receptor; FASTM; mutant tumor necrosis receptor superfamily member 6; RP11-399O19.9; TNF receptor superfamily member 6; TNFRSF6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily, member 6
Mus musculus (house mouse) : Fas (Fas (TNF receptor superfamily member 6))  MGI  Alliance
Rattus norvegicus (Norway rat) : Fas (Fas cell surface death receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fas (Fas cell surface death receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : FAS (Fas cell surface death receptor)
Canis lupus familiaris (dog) : FAS (Fas cell surface death receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fas (Fas cell surface death receptor)
Sus scrofa (pig) : FAS (Fas cell surface death receptor)
Chlorocebus sabaeus (African green monkey) : FAS (Fas cell surface death receptor)
Heterocephalus glaber (naked mole-rat) : Fas (Fas cell surface death receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: FAS (Gene ID: 355) and FASN (Gene ID: 2194) share the FAS symbol/alias in common. FAS is a widely used alternative name for fatty acid synthase (FASN), which can be confused with the official symbol for FAS (Fas cell surface death receptor, GeneID 355). [01 Jun 2018]
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1088,990,531 - 89,017,059 (+)Ensembl
GRCh381088,968,429 - 89,017,059 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371090,750,288 - 90,775,542 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361090,740,268 - 90,765,522 (+)NCBINCBI36hg18NCBI36
Build 341090,740,267 - 90,765,521NCBI
Celera1084,497,075 - 84,522,333 (+)NCBI
Cytogenetic Map10q23.31NCBI
HuRef1084,384,755 - 84,410,009 (+)NCBIHuRef
CHM1_11091,032,376 - 91,058,878 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression