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Gene: KIF11 (kinesin family member 11) Homo sapiens
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Symbol: KIF11
Name: kinesin family member 11
Description: Exhibits protein kinase binding activity. Involved in mitotic spindle assembly and regulation of mitotic centrosome separation. Localizes to the cytosol; microtubule cytoskeleton; and protein-containing complex. Colocalizes with the spindle microtubule and spindle pole. Implicated in microcephaly with or without chorioretinopathy, lymphedema, or mental retardation.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EG5; HKSP; kinesin-like 1; kinesin-like protein 1; kinesin-like protein KIF11; kinesin-like spindle protein HKSP; kinesin-related motor protein Eg5; KNSL1; MCLMR; thyroid receptor interacting protein 5; thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP-5; TRIP5
Orthologs:
Mus musculus (house mouse) : Kif11 (kinesin family member 11)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kif11 (kinesin family member 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kif11 (kinesin family member 11)
Pan paniscus (bonobo/pygmy chimpanzee) : KIF11 (kinesin family member 11)
Canis lupus familiaris (dog) : KIF11 (kinesin family member 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kif11 (kinesin family member 11)
Sus scrofa (pig) : KIF11 (kinesin family member 11)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1092,593,130 - 92,655,395 (+)Ensembl
GRCh381092,593,130 - 92,655,395 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371094,352,825 - 94,415,152 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361094,342,971 - 94,405,130 (+)NCBINCBI36hg18NCBI36
Build 341094,342,970 - 94,405,130NCBI
Celera1088,094,332 - 88,156,664 (+)NCBI
Cytogenetic Map10q23.33NCBI
HuRef1087,978,986 - 88,041,330 (+)NCBIHuRef
CHM1_11094,634,851 - 94,697,127 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on KIF11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346274
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.