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Gene: POU4F1 (POU class 4 homeobox 1) Homo sapiens
Symbol: POU4F1
Name: POU class 4 homeobox 1
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to the cytoplasm and nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: brain-3A; brain-specific homeobox/POU domain protein 3A; brn-3A; BRN3A; FLJ13449; homeobox/POU domain protein RDC-1; Oct-T1; POU domain, class 4, transcription factor 1; RDC-1
Mus musculus (house mouse) : Pou4f1 (POU domain, class 4, transcription factor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pou4f1 (POU class 4 homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pou4f1 (POU class 4 homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : POU4F1 (POU class 4 homeobox 1)
Canis lupus familiaris (dog) : POU4F1 (POU class 4 homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou4f1 (POU class 4 homeobox 1)
Sus scrofa (pig) : POU4F1 (POU class 4 homeobox 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381378,598,362 - 78,603,552 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371379,173,227 - 79,177,695 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361378,071,228 - 78,075,696 (-)NCBINCBI36hg18NCBI36
Build 341378,071,232 - 78,075,696NCBI
Celera1360,071,661 - 60,076,129 (-)NCBI
Cytogenetic Map13q31.1NCBI
HuRef1359,873,428 - 59,878,003 (-)NCBIHuRef
CHM1_11379,141,107 - 79,145,483 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on POU4F1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346307
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.