Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ADGRG4 (adhesion G protein-coupled receptor G4) Homo sapiens
Symbol: ADGRG4
Name: adhesion G protein-coupled receptor G4
Description: This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy. [provided by RefSeq, May 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adhesion G-protein coupled receptor G4; DKFZp781E1948; G protein-coupled receptor 112; GPR112; PGR17; probable G-protein coupled receptor 112; RP1-299I16
Mus musculus (house mouse) : Adgrg4 (adhesion G protein-coupled receptor G4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adgrg4 (adhesion G protein-coupled receptor G4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adgrg4 (adhesion G protein-coupled receptor G4)
Pan paniscus (bonobo/pygmy chimpanzee) : ADGRG4 (adhesion G protein-coupled receptor G4)
Canis lupus familiaris (dog) : ADGRG4 (adhesion G protein-coupled receptor G4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adgrg4 (adhesion G protein-coupled receptor G4)
Sus scrofa (pig) : ADGRG4 (adhesion G protein-coupled receptor G4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X136,300,963 - 136,416,888 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X135,383,122 - 135,499,047 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X135,210,788 - 135,326,713 (+)NCBINCBI36hg18NCBI36
Build 34X135,108,641 - 135,224,567NCBI
CeleraX135,745,772 - 135,861,718 (+)NCBI
Cytogenetic MapXq26.3NCBI
HuRefX124,653,324 - 124,769,965 (+)NCBIHuRef
CHM1_1X135,294,203 - 135,410,110 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ADGRG4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346347
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.