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Gene: PAGE4 (PAGE family member 4) Homo sapiens
Symbol: PAGE4
Name: PAGE family member 4
Description: This gene is a member of the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in prostate and prostate cancer. It is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer. The protein encoded by this gene shares sequence similarity with other GAGE/PAGE proteins, and also belongs to a family of CT (cancer-testis) antigens. The protein may play a role in benign and malignant prostate diseases. A related pseudogene is located on chromosome 7. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CT16.7; FLJ35184; G antigen family C member 1; G antigen, family C, 1; GAGE-9; GAGEC1; JM-27; JM27; P antigen family member 4; P antigen family, member 4 (prostate associated); PAGE-1; PAGE-4; prostate-associated gene 4 protein; prostate-associated gene protein 4
Pan paniscus (bonobo/pygmy chimpanzee) : PAGE4 (PAGE family member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Page4 (PAGE family member 4)
Sus scrofa (pig) : LOC100513450 (P antigen family member 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X49,829,260 - 49,834,264 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X49,593,863 - 49,598,572 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X49,480,644 - 49,485,308 (+)NCBINCBI36hg18NCBI36
Build 34X49,296,939 - 49,301,604NCBI
CeleraX53,663,213 - 53,667,877 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX47,063,025 - 47,067,690 (+)NCBIHuRef
CHM1_1X49,673,637 - 49,678,641 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PAGE4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346380
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.