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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Imported Annotations - CTD | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Liver Neoplasms | EXP | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:19233941 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| pre-malignant neoplasm | EXP | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:19233941 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene-Chemical Interaction AnnotationsGene Ontology AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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References - curated| 1. | GOA_HUMAN data from the GO Consortium |
| 2. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 3. | RGD automated import pipeline for gene-chemical interactions |
References - uncurated| PubMed | 8125298 8497321 8647288 10360579 10587647 10652228 10684602 10802735 10882715 11087735 11157984 11278436 11394904 11700021 11799118 12477932 12522270 14506255 14733946 15123659 15146197 15175157 15308621 15489334 15592455 15951569 15964811 16052498 16137687 16169070 16247015 16257963 16288044 16316319 16472662 16751776 16777958 17038317 17081983 17109515 17182860 17494760 18262180 18271526 18435854 18477472 18993068 19144635 19167335 19798056 19815557 19946888 20086093 20110370 20333297 20359967 20432460 20936779 20979614 21129804 21169560 21309750 21418896 21873635 21988832 22322295 22553920 22566699 22586264 22939624 22952966 23208506 23402884 23598414 23686771 23729439 23897914 24085293 24178904 24308962 24413169 24461128 25148682 25223282 25257795 25347744 25416956 25427824 25445114 25678401 25738261 25814554 25910212 25945695 26186194 26496610 26498357 26536663 26595808 26621748 26677978 27926694 28188290 28189676 28514442 28539360 28611215 28739485 28921811 29386546 |
Comparative Map Data| TNK2 (Homo sapiens - human) |
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| Tnk2 (Mus musculus - house mouse) |
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| Tnk2 (Rattus norvegicus - Norway rat) |
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| Tnk2 (Chinchilla lanigera - long-tailed chinchilla) |
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| TNK2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| TNK2 (Canis lupus familiaris - dog) |
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| Tnk2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| TNK2 (Sus scrofa - pig) |
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Position Markers| STS-R44803 |
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| D10S16 | No map positions available. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| ksks337 |
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| D8S2279 |
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| D8S2282 |
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| ksks336 |
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| D10S16 |
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miRNA Target Status
| The detailed report is available here: |  | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Nucleotide Sequences| RefSeq Transcripts | NG_029779 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| NM_001010938 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_001308046 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_005781 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_005269268 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_005269270 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_005269274 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_005269275 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011512317 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011512318 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011512320 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011512321 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017005508 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017005509 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017005510 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_024453291 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_024453292 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_024453293 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_024453294 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_024453295 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AB209338 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AC124944 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC245434 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AK024904 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AK126712 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AK127455 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AK131539 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AK225786 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AK309332 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC008884 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC020389 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC028164 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BE676668 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BG742978 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH471280 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CN411136 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| DQ596952 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| L13738 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_001010938 ⟹ NP_001010938 | |||||||||||||||||||||||||||||
| RefSeq Status: | REVIEWED | |||||||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
GGAGAGGAGGAACGGAGCTGGGACGGGCTGCAGGAGGGAATGGCCGCAGGCCGGCAGGAGGAGGhide sequence |
| RefSeq Acc Id: | NM_001308046 ⟹ NP_001294975 | ||||||||||||||
| RefSeq Status: | REVIEWED | ||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GTTGGGTGGGGAAGCCGGGGAGTAGGGCTGGACTGTGACCACTGCCCTGGAGAGAAGACAGAAAhide sequence |
| RefSeq Acc Id: | NM_005781 ⟹ NP_005772 | |||||||||||||||||||||||||||||
| RefSeq Status: | REVIEWED | |||||||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
GGGCCGGAAAGTTCCGGCGAACTGGGGGAGCGGCAGTGGGAGAGCGTCGGGCGGGAGGCGGTGGhide sequence |
| RefSeq Acc Id: | XM_005269268 ⟹ XP_005269325 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GGAGAGGAGGAACGGAGCTGGGACGGGCTGCAGGAGGGAATGGCCGCAGGCCGGCAGGAGGAGGhide sequence |
| RefSeq Acc Id: | XM_005269270 ⟹ XP_005269327 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
AGGATGTAGGGGCATGGGGAGTCGGGCGCAGAAGAGTGCGGGGAACCGCTGAGCTCTGGGAGCChide sequence |
| RefSeq Acc Id: | XM_005269274 ⟹ XP_005269331 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
CCGATGTCCTGAGCCAGCCAGAAGCCATGGACGACTTCATCCGGGAGGTCAATGCCATGCACTChide sequence |
| RefSeq Acc Id: | XM_005269275 ⟹ XP_005269332 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GACCACTGCCCTGGAGAGAAGACAGAAACAGGACAGAGGATCCCGGCTGCAGCCAGCGTGAGGAhide sequence |
| RefSeq Acc Id: | XM_011512317 ⟹ XP_011510619 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CCGGGATGCCTCGGAGGAGGGGGTCTCAGATGGAGTCGGACGGAGGCCCCTCTGCTGTGGGCTThide sequence |
| RefSeq Acc Id: | XM_011512318 ⟹ XP_011510620 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
ACCGGCCAGCTGTGGAAACCCAGCGGGGCTTGCAGCAGAGCGGAGGGGCCCACCCCGTTCTTCChide sequence |
| RefSeq Acc Id: | XM_011512320 ⟹ XP_011510622 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GCGGAGCCGGCTGAGCGCAGGGCCGAGCTGCGGGGCAGAGGCTGGGAGGCGGCAGAATGCAGCChide sequence |
| RefSeq Acc Id: | XM_011512321 ⟹ XP_011510623 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
TGAGGGTGGAGACAGACAGCACCAAATGGTCAGGCCAGAGAAGGGGCCAGGGCTAAAAATGGAChide sequence |
| RefSeq Acc Id: | XM_017005508 ⟹ XP_016860997 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
ACCGGCCAGCTGTGGAAACCCAGCGGGGCTTGCAGCAGAGCGGAGGGGCCCACCCCGTTCTTCChide sequence |
| RefSeq Acc Id: | XM_017005509 ⟹ XP_016860998 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
ACCGGCCAGCTGTGGAAACCCAGCGGGGCTTGCAGCAGAGCGGAGGGGCCCACCCCGTTCTTCChide sequence |
| RefSeq Acc Id: | XM_017005510 ⟹ XP_016860999 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
ACCGGCCAGCTGTGGAAACCCAGCGGGGCTTGCAGCAGAGCGGAGGGGCCCACCCCGTTCTTCChide sequence |
| RefSeq Acc Id: | XM_024453291 ⟹ XP_024309059 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GGCTGACTAAACTTGGTGGGGCTGACATGTGGAAGCAAGATAATCCTCTGGCTGGGGGAGGAGChide sequence |
| RefSeq Acc Id: | XM_024453292 ⟹ XP_024309060 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
|
|||||||||
| Sequence: |
TCCTGTTAGCTGGAGTTGGTGTGCTTGGAAGTGAGAGGCTGCAGGTCCCTGGCGAGAGCGTAGAhide sequence |
| RefSeq Acc Id: | XM_024453293 ⟹ XP_024309061 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
|
|||||||||
| Sequence: |
GCTGCGTGGAGATGCCGGCAGCACGTCGGTTCCCTGGCCTGGAGCTCTCCTTCCCTCTCCTGGChide sequence |
| RefSeq Acc Id: | XM_024453294 ⟹ XP_024309062 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
|
|||||||||
| Sequence: |
GGGACTGGTTGGGCTCCTCAGCACCAGCACTTGACTGAGAGGCAGAAAGCAAGACTGGGAGCGGhide sequence |
| RefSeq Acc Id: | XM_024453295 ⟹ XP_024309063 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
|
|||||||||
| Sequence: |
CCTCCTCCCCAGACCAGTGTGATGTCAGGCCCAGCCGACCTGAAGGTGCAGGGTTGCCTGGTGChide sequence |
Protein Sequences| Protein RefSeqs | NP_001010938 | (Get FASTA) | NCBI Sequence Viewer |
| NP_001294975 | (Get FASTA) | NCBI Sequence Viewer | |
| NP_005772 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_005269325 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_005269327 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_005269331 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_005269332 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011510619 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011510620 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011510622 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011510623 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_016860997 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_016860998 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_016860999 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_024309059 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_024309060 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_024309061 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_024309062 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_024309063 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAA53570 | (Get FASTA) | NCBI Sequence Viewer |
| AAH08884 | (Get FASTA) | NCBI Sequence Viewer | |
| AAH28164 | (Get FASTA) | NCBI Sequence Viewer | |
| BAD18675 | (Get FASTA) | NCBI Sequence Viewer | |
| BAD92575 | (Get FASTA) | NCBI Sequence Viewer | |
| BAG54506 | (Get FASTA) | NCBI Sequence Viewer | |
| EAW50333 | (Get FASTA) | NCBI Sequence Viewer | |
| EAW50334 | (Get FASTA) | NCBI Sequence Viewer | |
| EAW50335 | (Get FASTA) | NCBI Sequence Viewer | |
| EAW50336 | (Get FASTA) | NCBI Sequence Viewer | |
| EAW50337 | (Get FASTA) | NCBI Sequence Viewer | |
| Q07912 | (Get FASTA) | NCBI Sequence Viewer |
| RefSeq Acc Id: | NP_005772 ⟸ NM_005781 |
| - Peptide Label: | isoform 1 |
| - UniProtKB: | Q07912 (UniProtKB/Swiss-Prot), B3KXJ4 (UniProtKB/TrEMBL) |
| - Sequence: |
MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKhide sequence |
| RefSeq Acc Id: | NP_001010938 ⟸ NM_001010938 |
| - Peptide Label: | isoform 2 |
| - Sequence: |
MLEARPPRTQGSDAAGAAAGRGLRALLLSLTAAAGIWGSMGERSAYQRLAGGEEGPQRLGGGRMhide sequence |
| RefSeq Acc Id: | XP_005269327 ⟸ XM_005269270 |
| - Peptide Label: | isoform X9 |
| - Sequence: |
MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKhide sequence |
| RefSeq Acc Id: | XP_005269325 ⟸ XM_005269268 |
| - Peptide Label: | isoform X7 |
| - Sequence: |
MLEARPPRTQGSDAAGAAAGRGLRALLLSLTAAAGIWGSMGERSAYQRLAGGEEGPQRLGGGRMhide sequence |
| RefSeq Acc Id: | XP_005269332 ⟸ XM_005269275 |
| - Peptide Label: | isoform X12 |
| - Sequence: |
MFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFhide sequence |
| RefSeq Acc Id: | XP_005269331 ⟸ XM_005269274 |
| - Peptide Label: | isoform X11 |
| - Sequence: |
MGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKhide sequence |
| RefSeq Acc Id: | XP_011510622 ⟸ XM_011512320 |
| - Peptide Label: | isoform X9 |
| - Sequence: |
MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKhide sequence |
| RefSeq Acc Id: | XP_011510619 ⟸ XM_011512317 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MLEARPPRTQGSDAAGAAAGRGLRALLLSLTAAAGIWGSMGERSAYQRLAGGEEGPQLDYWASYhide sequence |
| RefSeq Acc Id: | XP_011510620 ⟸ XM_011512318 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MPAARRFPGLELSFPLLARLRRRLYTRLGGGRMQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVhide sequence |
| RefSeq Acc Id: | XP_011510623 ⟸ XM_011512321 |
| - Peptide Label: | isoform X10 |
| - Sequence: |
MRVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVhide sequence |
| RefSeq Acc Id: | NP_001294975 ⟸ NM_001308046 |
| - Peptide Label: | isoform 3 |
| - UniProtKB: | Q07912 (UniProtKB/Swiss-Prot), C9J1X3 (UniProtKB/TrEMBL) |
| - Sequence: |
MPAARRFPGLELSFPLLARLRRRLYTRLGGGRMQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVhide sequence |
| RefSeq Acc Id: | XP_016860997 ⟸ XM_017005508 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MPAARRFPGLELSFPLLARLRRRLYTRLGGGRMQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVhide sequence |
| RefSeq Acc Id: | XP_016860999 ⟸ XM_017005510 |
| - Peptide Label: | isoform X5 |
| - Sequence: |
MPAARRFPGLELSFPLLARLRRRLYTRLGGGRMQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVhide sequence |
| RefSeq Acc Id: | XP_016860998 ⟸ XM_017005509 |
| - Peptide Label: | isoform X4 |
| - Sequence: |
MPAARRFPGLELSFPLLARLRRRLYTRLGGGRMQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVhide sequence |
| RefSeq Acc Id: | XP_024309060 ⟸ XM_024453292 |
| - Peptide Label: | isoform X8 |
| - Sequence: |
MISGRKEGEQLRLGGGRMQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEhide sequence |
| RefSeq Acc Id: | XP_024309063 ⟸ XM_024453295 |
| - Peptide Label: | isoform X9 |
| - Sequence: |
MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKhide sequence |
| RefSeq Acc Id: | XP_024309059 ⟸ XM_024453291 |
| - Peptide Label: | isoform X6 |
| - Sequence: |
MRSGALGPRGRGRASALGLPVPAMASRQCWARHPRVGLCWAAFEQESGPSCHRSEVKERLGGGRhide sequence |
| RefSeq Acc Id: | XP_024309061 ⟸ XM_024453293 |
| - Peptide Label: | isoform X9 |
| - Sequence: |
MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKhide sequence |
| RefSeq Acc Id: | XP_024309062 ⟸ XM_024453294 |
| - Peptide Label: | isoform X9 |
| - Sequence: |
MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKhide sequence |
Promoters| RGD ID: | 6866668 | |||||||||
| Promoter ID: | EPDNEW_H6498 | |||||||||
| Type: | initiation region | |||||||||
| Name: | TNK2_2 | |||||||||
| Description: | tyrosine kinase non receptor 2 | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
|
| RGD ID: | 6866670 | |||||||||
| Promoter ID: | EPDNEW_H6499 | |||||||||
| Type: | initiation region | |||||||||
| Name: | TNK2_3 | |||||||||
| Description: | tyrosine kinase non receptor 2 | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
|
| RGD ID: | 6866672 | |||||||||
| Promoter ID: | EPDNEW_H6500 | |||||||||
| Type: | initiation region | |||||||||
| Name: | TNK2_4 | |||||||||
| Description: | tyrosine kinase non receptor 2 | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
|
| RGD ID: | 6866674 | |||||||||
| Promoter ID: | EPDNEW_H6501 | |||||||||
| Type: | initiation region | |||||||||
| Name: | TNK2_1 | |||||||||
| Description: | tyrosine kinase non receptor 2 | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
|
| RGD ID: | 6801806 | |||||||||
| Promoter ID: | HG_KWN:47424 | |||||||||
| Type: | CpG-Island | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | MPROMDB | |||||||||
| Tissues & Cell Lines: | Lymphoblastoid | |||||||||
| Transcripts: | OTTHUMT00000341446, OTTHUMT00000341512 | |||||||||
| Position: |
|
| RGD ID: | 6801813 | |||||||||
| Promoter ID: | HG_KWN:47426 | |||||||||
| Type: | CpG-Island | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | MPROMDB | |||||||||
| Tissues & Cell Lines: | HeLa_S3, K562 | |||||||||
| Transcripts: | OTTHUMT00000341507, OTTHUMT00000341508, OTTHUMT00000341509 | |||||||||
| Position: |
|
| RGD ID: | 6801814 | |||||||||
| Promoter ID: | HG_KWN:47428 | |||||||||
| Type: | CpG-Island | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | MPROMDB | |||||||||
| Tissues & Cell Lines: | Lymphoblastoid | |||||||||
| Transcripts: | OTTHUMT00000341505, UC003FVV.1 | |||||||||
| Position: |
|
| RGD ID: | 6801810 | |||||||||
| Promoter ID: | HG_KWN:47429 | |||||||||
| Type: | CpG-Island | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | MPROMDB | |||||||||
| Tissues & Cell Lines: | Lymphoblastoid | |||||||||
| Transcripts: | OTTHUMT00000341504 | |||||||||
| Position: |
|
| RGD ID: | 6801812 | |||||||||
| Promoter ID: | HG_KWN:47430 | |||||||||
| Type: | CpG-Island | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | MPROMDB | |||||||||
| Tissues & Cell Lines: | HeLa_S3, K562, Lymphoblastoid | |||||||||
| Transcripts: | OTTHUMT00000341441, OTTHUMT00000341442, OTTHUMT00000341503 | |||||||||
| Position: |
|
| RGD ID: | 6801811 | |||||||||
| Promoter ID: | HG_KWN:47431 | |||||||||
| Type: | CpG-Island | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | MPROMDB | |||||||||
| Tissues & Cell Lines: | CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, K562, Lymphoblastoid, NB4 | |||||||||
| Transcripts: | OTTHUMT00000341502 | |||||||||
| Position: |
|
| RGD ID: | 6800899 | |||||||||
| Promoter ID: | HG_KWN:47432 | |||||||||
| Type: | CpG-Island | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | MPROMDB | |||||||||
| Tissues & Cell Lines: | CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, HeLa_S3, K562, Lymphoblastoid, NB4 | |||||||||
| Transcripts: | ENST00000316664, ENST00000392400, OTTHUMT00000341440, OTTHUMT00000341501, UC010HZW.1 | |||||||||
| Position: |
|
| RGD ID: | 6801809 | |||||||||
| Promoter ID: | HG_KWN:47433 | |||||||||
| Type: | CpG-Island | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | MPROMDB | |||||||||
| Tissues & Cell Lines: | Lymphoblastoid | |||||||||
| Transcripts: | OTTHUMT00000341500 | |||||||||
| Position: |
|
| RGD ID: | 6801807 | |||||||||
| Promoter ID: | HG_KWN:47435 | |||||||||
| Type: | CpG-Island | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | MPROMDB | |||||||||
| Tissues & Cell Lines: | CD4+TCell, CD4+TCell_12Hour, HeLa_S3, K562, Lymphoblastoid, NB4 | |||||||||
| Transcripts: | OTTHUMT00000341437 | |||||||||
| Position: |
|
| RGD ID: | 6800565 | |||||||||
| Promoter ID: | HG_KWN:47436 | |||||||||
| Type: | Non-CpG | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | MPROMDB | |||||||||
| Tissues & Cell Lines: | HeLa_S3 | |||||||||
| Transcripts: | OTTHUMT00000341874, OTTHUMT00000341875, UC010HZX.1 | |||||||||
| Position: |
|
Clinical Variants| Name | Type | Condition(s) | Position(s) | Clinical significance |
| GRCh37/hg19 3q29(chr3:195457650-196263123) | copy number loss | Autistic disorder of childhood onset [RCV000626534] | Chr3:195457650..196263123 [GRCh37] Chr3:3q29 |
uncertain significance |
| NM_005781.4(TNK2):c.1912G>A (p.Val638Met) | single nucleotide variant | Autosomal recessive infantile epilepsy [RCV000074437]|Parkinson disease [RCV000210440] | Chr3:195868341 [GRCh38] Chr3:195595212 [GRCh37] Chr3:3q29 |
uncertain significance |
| GRCh38/hg38 3q27.2-29(chr3:185485849-198110178)x1 | copy number loss | Global developmental delay [RCV000051608]|See cases [RCV000051608] | Chr3:185485849..198110178 [GRCh38] Chr3:185203637..197837049 [GRCh37] Chr3:186686331..199321446 [NCBI36] Chr3:3q27.2-29 |
pathogenic |
| GRCh38/hg38 3q24-29(chr3:147521892-198096565)x3 | copy number gain | Abnormality of the heart [RCV000051725]|See cases [RCV000051725] | Chr3:147521892..198096565 [GRCh38] Chr3:147239679..197823436 [GRCh37] Chr3:148722369..199307833 [NCBI36] Chr3:3q24-29 |
pathogenic |
| GRCh38/hg38 3q25.31-29(chr3:157293378-198134727)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051726]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051726]|See cases [RCV000051726] | Chr3:157293378..198134727 [GRCh38] Chr3:157011167..197861598 [GRCh37] Chr3:158493861..199345995 [NCBI36] Chr3:3q25.31-29 |
pathogenic |
| GRCh38/hg38 3q26.32-29(chr3:178411707-198110319)x3 | copy number gain | Abnormal facial shape [RCV000051736]|See cases [RCV000051736] | Chr3:178411707..198110319 [GRCh38] Chr3:178129495..197837190 [GRCh37] Chr3:179612189..199321587 [NCBI36] Chr3:3q26.32-29 |
pathogenic |
| GRCh38/hg38 3q27.2-29(chr3:185920880-198110319)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051738]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051738]|See cases [RCV000051738] | Chr3:185920880..198110319 [GRCh38] Chr3:185638668..197837190 [GRCh37] Chr3:187121362..199321587 [NCBI36] Chr3:3q27.2-29 |
pathogenic |
| GRCh38/hg38 3q28-29(chr3:189265371-198110178)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051739]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051739]|See cases [RCV000051739] | Chr3:189265371..198110178 [GRCh38] Chr3:188983160..197837049 [GRCh37] Chr3:190465854..199321446 [NCBI36] Chr3:3q28-29 |
pathogenic |
| GRCh38/hg38 3q28-29(chr3:190667663-198110178)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051740]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051740]|See cases [RCV000051740] | Chr3:190667663..198110178 [GRCh38] Chr3:190385452..197837049 [GRCh37] Chr3:191868146..199321446 [NCBI36] Chr3:3q28-29 |
pathogenic |
| GRCh38/hg38 3q29(chr3:193917490-198110319)x3 | copy number gain | Abnormality of the foot [RCV000051741]|See cases [RCV000051741] | Chr3:193917490..198110319 [GRCh38] Chr3:193635279..197837190 [GRCh37] Chr3:195117973..199321587 [NCBI36] Chr3:3q29 |
pathogenic |
| GRCh38/hg38 3q29(chr3:194424496-198168758)x3 | copy number gain | Telecanthus [RCV000051742]|See cases [RCV000051742] | Chr3:194424496..198168758 [GRCh38] Chr3:194145225..197895629 [GRCh37] Chr3:195626514..199380026 [NCBI36] Chr3:3q29 |
pathogenic |
| GRCh38/hg38 3q22.3-29(chr3:137126982-198110178)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051723]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051723]|See cases [RCV000051723] | Chr3:137126982..198110178 [GRCh38] Chr3:136845824..197837049 [GRCh37] Chr3:138328514..199321446 [NCBI36] Chr3:3q22.3-29 |
pathogenic |
| GRCh38/hg38 3q29(chr3:195896948-198110178)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053541]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053541]|See cases [RCV000053541] | Chr3:195896948..198110178 [GRCh38] Chr3:195623819..197837049 [GRCh37] Chr3:197108216..199321446 [NCBI36] Chr3:3q29 |
uncertain significance |
| GRCh38/hg38 3q29(chr3:195711798-197976152)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053540]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053540]|See cases [RCV000053540] | Chr3:195711798..197976152 [GRCh38] Chr3:195438669..197703023 [GRCh37] Chr3:196924340..199187420 [NCBI36] Chr3:3q29 |
uncertain significance |
| GRCh38/hg38 3q29(chr3:195755702-197583580)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053853]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053853]|See cases [RCV000053853] | Chr3:195755702..197583580 [GRCh38] Chr3:195482573..197310451 [GRCh37] Chr3:196968244..198794848 [NCBI36] Chr3:3q29 |
pathogenic|uncertain significance |
| NM_005781.4(TNK2):c.1053C>T (p.Pro351=) | single nucleotide variant | Malignant melanoma [RCV000065993] | Chr3:195878554 [GRCh38] Chr3:195605425 [GRCh37] Chr3:197089822 [NCBI36] Chr3:3q29 |
not provided |
| GRCh38/hg38 3q13.11-29(chr3:103426882-198110178)x3 | copy number gain | See cases [RCV000134948] | Chr3:103426882..198110178 [GRCh38] Chr3:103145726..197837049 [GRCh37] Chr3:104628416..199321446 [NCBI36] Chr3:3q13.11-29 |
pathogenic |
| GRCh38/hg38 3q29(chr3:195896948-195937261)x3 | copy number gain | See cases [RCV000135119] | Chr3:195896948..195937261 [GRCh38] Chr3:195623819..195664132 [GRCh37] Chr3:197108216..197148529 [NCBI36] Chr3:3q29 |
benign |
| GRCh38/hg38 3q29(chr3:195838288-196013545)x1 | copy number loss | See cases [RCV000135561] | Chr3:195838288..196013545 [GRCh38] Chr3:195565159..195740416 [GRCh37] Chr3:197049556..197224813 [NCBI36] Chr3:3q29 |
likely benign|uncertain significance |
| GRCh38/hg38 3q29(chr3:194338534-197693741)x1 | copy number loss | See cases [RCV000136517] | Chr3:194338534..197693741 [GRCh38] Chr3:194059263..197420612 [GRCh37] Chr3:195540958..198905009 [NCBI36] Chr3:3q29 |
pathogenic|uncertain significance |
| GRCh38/hg38 3q26.2-29(chr3:168167568-198110178)x3 | copy number gain | See cases [RCV000137106] | Chr3:168167568..198110178 [GRCh38] Chr3:167885356..197837049 [GRCh37] Chr3:169368050..199321446 [NCBI36] Chr3:3q26.2-29 |
pathogenic |
| GRCh38/hg38 3q29(chr3:195711798-198110178)x3 | copy number gain | See cases [RCV000137110] | Chr3:195711798..198110178 [GRCh38] Chr3:195438669..197837049 [GRCh37] Chr3:196924340..199321446 [NCBI36] Chr3:3q29 |
pathogenic |
| GRCh38/hg38 3q26.32-29(chr3:176439911-198118383)x3 | copy number gain | See cases [RCV000138009] | Chr3:176439911..198118383 [GRCh38] Chr3:176157699..197845254 [GRCh37] Chr3:177640393..199329651 [NCBI36] Chr3:3q26.32-29 |
pathogenic|likely benign |
| GRCh38/hg38 3q29(chr3:192752937-198118383)x3 | copy number gain | See cases [RCV000137827] | Chr3:192752937..198118383 [GRCh38] Chr3:192470726..197845254 [GRCh37] Chr3:193953420..199329651 [NCBI36] Chr3:3q29 |
pathogenic |
| GRCh38/hg38 3q26.32-29(chr3:176168525-198118383)x3 | copy number gain | See cases [RCV000138662] | Chr3:176168525..198118383 [GRCh38] Chr3:175886313..197845254 [GRCh37] Chr3:177369007..199329651 [NCBI36] Chr3:3q26.32-29 |
pathogenic |
| GRCh38/hg38 3q29(chr3:194296197-198110198)x3 | copy number gain | See cases [RCV000138492] | Chr3:194296197..198110198 [GRCh38] Chr3:194013986..197837069 [GRCh37] Chr3:195496680..199321466 [NCBI36] Chr3:3q29 |
pathogenic |
| GRCh38/hg38 3q25.1-29(chr3:152100512-198118383)x3 | copy number gain | See cases [RCV000139435] | Chr3:152100512..198118383 [GRCh38] Chr3:151818301..197845254 [GRCh37] Chr3:153300991..199329651 [NCBI36] Chr3:3q25.1-29 |
pathogenic |
| GRCh38/hg38 3q25.31-29(chr3:156321878-198113452)x3 | copy number gain | See cases [RCV000140849] | Chr3:156321878..198113452 [GRCh38] Chr3:156039667..197840323 [GRCh37] Chr3:157522361..199324720 [NCBI36] Chr3:3q25.31-29 |
pathogenic |
| GRCh38/hg38 3q29(chr3:195838288-195918665)x3 | copy number gain | See cases [RCV000140997] | Chr3:195838288..195918665 [GRCh38] Chr3:195565159..195645536 [GRCh37] Chr3:197049556..197129933 [NCBI36] Chr3:3q29 |
benign |
| GRCh38/hg38 3q25.31-29(chr3:156118441-198125115)x3 | copy number gain | See cases [RCV000142310] | Chr3:156118441..198125115 [GRCh38] Chr3:155836230..197851986 [GRCh37] Chr3:157318924..199336383 [NCBI36] Chr3:3q25.31-29 |
pathogenic |
| GRCh38/hg38 3q26.1-29(chr3:166137209-198125115)x3 | copy number gain | See cases [RCV000143694] | Chr3:166137209..198125115 [GRCh38] Chr3:165854997..197851986 [GRCh37] Chr3:167337691..199336383 [NCBI36] Chr3:3q26.1-29 |
pathogenic |
| GRCh38/hg38 3q29(chr3:193704605-198125115)x3 | copy number gain | See cases [RCV000143501] | Chr3:193704605..198125115 [GRCh38] Chr3:193422394..197851986 [GRCh37] Chr3:194905088..199336383 [NCBI36] Chr3:3q29 |
pathogenic |
| NM_005781.4(TNK2):c.1732G>A (p.Val578Met) | single nucleotide variant | Abnormality of neuronal migration [RCV000201369] | Chr3:195868521 [GRCh38] Chr3:195595392 [GRCh37] Chr3:3q29 |
benign |
| NM_005781.4(TNK2):c.766C>T (p.Arg256Cys) | single nucleotide variant | Abnormality of neuronal migration [RCV000201409] | Chr3:195882172 [GRCh38] Chr3:195609043 [GRCh37] Chr3:3q29 |
pathogenic|benign |
| NM_005781.4(TNK2):c.2630G>A (p.Arg877His) | single nucleotide variant | Parkinson disease [RCV000210436]|not specified [RCV000254280] | Chr3:195867623 [GRCh38] Chr3:195594494 [GRCh37] Chr3:3q29 |
likely pathogenic|benign |
| NM_005781.4(TNK2):c.2930C>T (p.Ala977Val) | single nucleotide variant | Parkinson disease [RCV000210443] | Chr3:195867221 [GRCh38] Chr3:195594092 [GRCh37] Chr3:3q29 |
uncertain significance |
| NM_005781.4(TNK2):c.1088T>C (p.Val363Ala) | single nucleotide variant | Parkinson disease [RCV000210445] | Chr3:195878519 [GRCh38] Chr3:195605390 [GRCh37] Chr3:3q29 |
uncertain significance |
| NM_005781.4(TNK2):c.2174C>T (p.Pro725Leu) | single nucleotide variant | not specified [RCV000246369] | Chr3:195868079 [GRCh38] Chr3:195594950 [GRCh37] Chr3:3q29 |
benign |
| NM_005781.4(TNK2):c.1719C>T (p.Phe573=) | single nucleotide variant | not specified [RCV000251607] | Chr3:195868534 [GRCh38] Chr3:195595405 [GRCh37] Chr3:3q29 |
benign |
| NM_005781.4(TNK2):c.2319T>C (p.Ala773=) | single nucleotide variant | not specified [RCV000249289] | Chr3:195867934 [GRCh38] Chr3:195594805 [GRCh37] Chr3:3q29 |
benign |
| NM_005781.4(TNK2):c.2163G>A (p.Pro721=) | single nucleotide variant | not specified [RCV000254358] | Chr3:195868090 [GRCh38] Chr3:195594961 [GRCh37] Chr3:3q29 |
likely benign |
| NM_005781.4(TNK2):c.915C>T (p.Arg305=) | single nucleotide variant | not specified [RCV000242298] | Chr3:195879148 [GRCh38] Chr3:195606019 [GRCh37] Chr3:3q29 |
benign |
| NM_005781.4(TNK2):c.351C>T (p.Leu117=) | single nucleotide variant | not specified [RCV000242397] | Chr3:195884917 [GRCh38] Chr3:195611788 [GRCh37] Chr3:3q29 |
benign |
| NM_005781.4(TNK2):c.84T>C (p.Asp28=) | single nucleotide variant | not specified [RCV000250321] | Chr3:195888505 [GRCh38] Chr3:195615376 [GRCh37] Chr3:3q29 |
benign |
| NM_005781.4(TNK2):c.2070G>A (p.Pro690=) | single nucleotide variant | not specified [RCV000243185] | Chr3:195868183 [GRCh38] Chr3:195595054 [GRCh37] Chr3:3q29 |
benign |
| NM_005781.4(TNK2):c.843C>T (p.Asp281=) | single nucleotide variant | not specified [RCV000245783] | Chr3:195882095 [GRCh38] Chr3:195608966 [GRCh37] Chr3:3q29 |
likely benign |
| NM_005781.4(TNK2):c.2095A>G (p.Ser699Gly) | single nucleotide variant | not specified [RCV000248150] | Chr3:195868158 [GRCh38] Chr3:195595029 [GRCh37] Chr3:3q29 |
likely benign |
| NM_005781.4(TNK2):c.2668G>A (p.Val890Met) | single nucleotide variant | not specified [RCV000245873] | Chr3:195867585 [GRCh38] Chr3:195594456 [GRCh37] Chr3:3q29 |
likely benign |
| NM_005781.4(TNK2):c.1029C>T (p.Ile343=) | single nucleotide variant | not specified [RCV000248262] | Chr3:195878578 [GRCh38] Chr3:195605449 [GRCh37] Chr3:3q29 |
likely benign |
| NM_005781.4(TNK2):c.3113G>A (p.Arg1038His) | single nucleotide variant | not specified [RCV000250824] | Chr3:195864185 [GRCh38] Chr3:195591056 [GRCh37] Chr3:3q29 |
benign |
| NM_005781.4(TNK2):c.405T>C (p.Gly135=) | single nucleotide variant | not provided [RCV000487972] | Chr3:195884863 [GRCh38] Chr3:195611734 [GRCh37] Chr3:3q29 |
uncertain significance |
| NM_005781.4(TNK2):c.63G>T (p.Gln21His) | single nucleotide variant | not provided [RCV000488358] | Chr3:195888526 [GRCh38] Chr3:195615397 [GRCh37] Chr3:3q29 |
uncertain significance |
| NM_005781.4(TNK2):c.1015-2A>G | single nucleotide variant | not specified [RCV000414302] | Chr3:195878594 [GRCh38] Chr3:195605465 [GRCh37] Chr3:3q29 |
uncertain significance |
| NM_005781.4(TNK2):c.2896A>T (p.Met966Leu) | single nucleotide variant | not specified [RCV000413786] | Chr3:195867255 [GRCh38] Chr3:195594126 [GRCh37] Chr3:3q29 |
uncertain significance |
| GRCh37/hg19 3q25.32-29(chr3:158980631-197766890)x3 | copy number gain | See cases [RCV000447464] | Chr3:158980631..197766890 [GRCh37] Chr3:3q25.32-29 |
pathogenic |
| GRCh37/hg19 3q26.33-29(chr3:181911498-197851986)x4 | copy number gain | See cases [RCV000446732] | Chr3:181911498..197851986 [GRCh37] Chr3:3q26.33-29 |
pathogenic |
| GRCh37/hg19 3q25.2-29(chr3:152356847-197851986)x3 | copy number gain | See cases [RCV000448608] | Chr3:152356847..197851986 [GRCh37] Chr3:3q25.2-29 |
pathogenic |
| GRCh37/hg19 3q29(chr3:195456034-197851986)x3 | copy number gain | See cases [RCV000448647] | Chr3:195456034..197851986 [GRCh37] Chr3:3q29 |
pathogenic |
| GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 | copy number gain | See cases [RCV000511055] | Chr3:61892..197851986 [GRCh37] Chr3:3p26.3-q29 |
pathogenic |
| GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) | copy number gain | See cases [RCV000512358] | Chr3:61892..197851986 [GRCh37] Chr3:3p26.3-q29 |
pathogenic |
| GRCh37/hg19 3q29(chr3:195456034-197356334)x3 | copy number gain | See cases [RCV000512582] | Chr3:195456034..197356334 [GRCh37] Chr3:3q29 |
uncertain significance |
| GRCh37/hg19 3q27.1-29(chr3:184003967-197851986)x3 | copy number gain | not provided [RCV000682339] | Chr3:184003967..197851986 [GRCh37] Chr3:3q27.1-29 |
pathogenic |
| GRCh37/hg19 3q26.33-29(chr3:182539234-197851986)x3 | copy number gain | not provided [RCV000682336] | Chr3:182539234..197851986 [GRCh37] Chr3:3q26.33-29 |
pathogenic |
| GRCh37/hg19 3q28-29(chr3:187913567-197851986)x3 | copy number gain | not provided [RCV000682344] | Chr3:187913567..197851986 [GRCh37] Chr3:3q28-29 |
pathogenic |
| GRCh37/hg19 3q28-29(chr3:191593619-197851986)x3 | copy number gain | not provided [RCV000682346] | Chr3:191593619..197851986 [GRCh37] Chr3:3q28-29 |
pathogenic |
| GRCh37/hg19 3q27.3-29(chr3:186374365-197851986)x3 | copy number gain | not provided [RCV000682341] | Chr3:186374365..197851986 [GRCh37] Chr3:3q27.3-29 |
pathogenic |
| GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 | copy number gain | not provided [RCV000742138] | Chr3:61495..197838262 [GRCh37] Chr3:3p26.3-q29 |
pathogenic |
| GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 | copy number gain | not provided [RCV000742133] | Chr3:60174..197948027 [GRCh37] Chr3:3p26.3-q29 |
pathogenic |
| GRCh37/hg19 3q26.31-29(chr3:173281266-197838262)x3 | copy number gain | not provided [RCV000742968] | Chr3:173281266..197838262 [GRCh37] Chr3:3q26.31-29 |
pathogenic |
| GRCh37/hg19 3q27.3-29(chr3:186374671-197838262)x3 | copy number gain | not provided [RCV000743037] | Chr3:186374671..197838262 [GRCh37] Chr3:3q27.3-29 |
pathogenic |
| GRCh37/hg19 3q28-29(chr3:189101446-197838262)x1 | copy number loss | not provided [RCV000743049] | Chr3:189101446..197838262 [GRCh37] Chr3:3q28-29 |
pathogenic |
| GRCh37/hg19 3q29(chr3:195557461-195778594)x3 | copy number gain | not provided [RCV000743102] | Chr3:195557461..195778594 [GRCh37] Chr3:3q29 |
benign |
| GRCh37/hg19 3q29(chr3:195635686-195638506)x1 | copy number loss | not provided [RCV000743103] | Chr3:195635686..195638506 [GRCh37] Chr3:3q29 |
benign |
| GRCh37/hg19 3q29(chr3:195635804-195752770)x3 | copy number gain | not provided [RCV000743104] | Chr3:195635804..195752770 [GRCh37] Chr3:3q29 |
benign |
| GRCh37/hg19 3q29(chr3:195635847-195638506)x0 | copy number loss | not provided [RCV000743105] | Chr3:195635847..195638506 [GRCh37] Chr3:3q29 |
benign |
| GRCh37/hg19 3q28-29(chr3:188386566-197838262)x3 | copy number gain | See cases [RCV000790566] | Chr3:188386566..197838262 [GRCh37] Chr3:3q28-29 |
pathogenic |
| GRCh37/hg19 3q29(chr3:195482356-195649175)x1 | copy number loss | not provided [RCV000848117] | Chr3:195482356..195649175 [GRCh37] Chr3:3q29 |
uncertain significance |
| GRCh37/hg19 3q29(chr3:195464080-195705980)x3 | copy number gain | not provided [RCV000848869] | Chr3:195464080..195705980 [GRCh37] Chr3:3q29 |
uncertain significance |
| GRCh37/hg19 3q29(chr3:195573221-196124278)x3 | copy number gain | not provided [RCV000847985] | Chr3:195573221..196124278 [GRCh37] Chr3:3q29 |
uncertain significance |
| GRCh37/hg19 3q29(chr3:195279196-196022437)x3 | copy number gain | not provided [RCV000846857] | Chr3:195279196..196022437 [GRCh37] Chr3:3q29 |
uncertain significance |
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | HGNC:19297 | AgrOrtholog |
| COSMIC | TNK2 | COSMIC |
| Ensembl Genes | ENSG00000061938 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSP00000329425 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSP00000371341 | UniProtKB/TrEMBL | |
| ENSP00000392546 | ENTREZGENE, UniProtKB/TrEMBL | |
| ENSP00000395588 | UniProtKB/Swiss-Prot | |
| ENSP00000499858 | ENTREZGENE | |
| ENSP00000499899 | ENTREZGENE | |
| ENSP00000500452 | ENTREZGENE | |
| Ensembl Transcript | ENST00000333602 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENST00000381916 | UniProtKB/TrEMBL | |
| ENST00000428187 | ENTREZGENE, UniProtKB/TrEMBL | |
| ENST00000439230 | UniProtKB/Swiss-Prot | |
| ENST00000671753 | ENTREZGENE | |
| ENST00000672887 | ENTREZGENE | |
| ENST00000673038 | ENTREZGENE | |
| Gene3D-CATH | 4.10.680.10 | UniProtKB/Swiss-Prot |
| GTEx | ENSG00000061938 | GTEx |
| HGNC ID | HGNC:19297 | ENTREZGENE |
| Human Proteome Map | TNK2 | Human Proteome Map |
| InterPro | Ack1 | UniProtKB/Swiss-Prot |
| Cdc42-bd-like_dom_sf | UniProtKB/Swiss-Prot | |
| Cdc42_binding_dom-like | UniProtKB/Swiss-Prot | |
| Kinase-like_dom_sf | UniProtKB/Swiss-Prot | |
| Mig-6 | UniProtKB/Swiss-Prot | |
| Prot_kinase_dom | UniProtKB/Swiss-Prot | |
| Protein_kinase_ATP_BS | UniProtKB/Swiss-Prot | |
| Ser-Thr/Tyr_kinase_cat_dom | UniProtKB/Swiss-Prot | |
| SH3-like_dom_sf | UniProtKB/Swiss-Prot | |
| SH3_domain | UniProtKB/Swiss-Prot | |
| Tyr_kinase_AS | UniProtKB/Swiss-Prot | |
| Tyr_kinase_cat_dom | UniProtKB/Swiss-Prot | |
| UBA-like | UniProtKB/TrEMBL | |
| KEGG Report | hsa:10188 | UniProtKB/Swiss-Prot |
| NCBI Gene | 10188 | ENTREZGENE |
| OMIM | 606994 | OMIM |
| PANTHER | PTHR14254:SF6 | UniProtKB/Swiss-Prot |
| Pfam | GTPase_binding | UniProtKB/Swiss-Prot |
| Inhibitor_Mig-6 | UniProtKB/Swiss-Prot | |
| Pkinase_Tyr | UniProtKB/Swiss-Prot | |
| SH3_9 | UniProtKB/Swiss-Prot | |
| PharmGKB | PA134909759 | PharmGKB |
| PRINTS | TYRKINASE | UniProtKB/Swiss-Prot |
| PROSITE | PROTEIN_KINASE_ATP | UniProtKB/Swiss-Prot |
| PROTEIN_KINASE_DOM | UniProtKB/Swiss-Prot | |
| PROTEIN_KINASE_TYR | UniProtKB/Swiss-Prot | |
| SH3 | UniProtKB/Swiss-Prot | |
| SMART | SH3 | UniProtKB/Swiss-Prot |
| TyrKc | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | SSF46934 | UniProtKB/TrEMBL |
| SSF50044 | UniProtKB/Swiss-Prot | |
| SSF56112 | UniProtKB/Swiss-Prot | |
| UniGene | Hs.518513 | ENTREZGENE |
| UniProt | A0A499FJ16_HUMAN | UniProtKB/TrEMBL |
| ACK1_HUMAN | UniProtKB/Swiss-Prot | |
| B3KXJ4 | ENTREZGENE, UniProtKB/TrEMBL | |
| C9J1X3 | ENTREZGENE, UniProtKB/TrEMBL | |
| Q07912 | ENTREZGENE | |
| UniProt Secondary | Q6ZMQ0 | UniProtKB/Swiss-Prot |
| Q8N6U7 | UniProtKB/Swiss-Prot | |
| Q96H59 | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2016-05-03 | TNK2 | tyrosine kinase non receptor 2 | tyrosine kinase, non-receptor, 2 | Symbol and/or name change | 5135510 | APPROVED | |
| 2011-08-16 | TNK2 | tyrosine kinase, non-receptor, 2 | TNK2 | tyrosine kinase, non-receptor, 2 | Symbol and/or name change | 5135510 | APPROVED |
 |
| More on TNK2 | |
|
Alliance Gene |
|
NCBI Gene |
|
Ensembl Gene |
|
|
JBrowse: hg19 hg38 |
|
HGNC Report |
|
NCBI Genome Data Viewer |
| CRRD Object Information | |
| CRRD ID: | 1346409 |
| Created: | 2005-03-08 |
| Species: | Homo sapiens |
| Last Modified: | 2019-11-26 |
| Status: | ACTIVE |
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.
