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Gene: H2AX (H2A.X variant histone) Homo sapiens
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Symbol: H2AX
Name: H2A.X variant histone
Description: Exhibits enzyme binding activity and histone binding activity. Involved in DNA damage checkpoint. Localizes to centrosome; nuclear speck; and site of double-strand break. Colocalizes with chromosome, telomeric region.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H2A histone family member X; H2A histone family, member X; H2A.X; H2A/X; H2AFX; H2AX histone; histone H2A.x; histone H2AX
Orthologs:
Mus musculus (house mouse) : H2ax (H2A.X variant histone)  MGI  Alliance
Rattus norvegicus (Norway rat) : H2ax (H2A.X variant histone)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102025775 (histone H2AX)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100994157 (histone H2AX)
Canis lupus familiaris (dog) : H2AX (H2A.X variant histone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101966907 (histone H2AX)
Sus scrofa (pig) : LOC100522201 (histone H2AX)
Chlorocebus sabaeus (African green monkey) : H2AFX (histone H2AX)
Heterocephalus glaber (naked mole-rat) : LOC101701891 (histone H2AX)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11119,093,854 - 119,095,467 (-)EnsemblGRCh38hg38GRCh38
GRCh3811119,093,874 - 119,095,465 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711118,964,580 - 118,966,177 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,469,794 - 118,471,387 (-)NCBINCBI36hg18NCBI36
Build 3411118,469,796 - 118,471,387NCBI
Celera11116,121,998 - 116,123,592 (-)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11114,904,032 - 114,905,625 (-)NCBIHuRef
CHM1_111118,850,886 - 118,852,479 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on H2AX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346464
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.