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Gene: CDK9 (cyclin dependent kinase 9) Homo sapiens
Symbol: CDK9
Name: cyclin dependent kinase 9
Description: Exhibits nucleic acid binding activity; protein serine/threonine kinase activity; and transcription coactivator binding activity. Involved in several processes, including negative regulation of cell cycle arrest; positive regulation of histone modification; and regulation of nucleobase-containing compound metabolic process. Localizes to the PML body; cyclin/CDK positive transcription elongation factor complex; and cytoplasmic ribonucleoprotein granule. Biomarker of congestive heart failure.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-2k; CDC2-related kinase; CDC2L4; cell division cycle 2-like protein kinase 4; cell division protein kinase 9; CTK1; cyclin-dependent kinase 9; PITALRE; serine/threonine protein kinase PITALRE; serine/threonine-protein kinase PITALRE; TAK; tat-associated kinase complex catalytic subunit
Mus musculus (house mouse) : Cdk9 (cyclin-dependent kinase 9 (CDC2-related kinase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdk9 (cyclin-dependent kinase 9)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk9 (cyclin dependent kinase 9)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK9 (cyclin dependent kinase 9)
Canis lupus familiaris (dog) : CDK9 (cyclin dependent kinase 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk9 (cyclin dependent kinase 9)
Sus scrofa (pig) : CDK9 (cyclin dependent kinase 9)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389127,786,034 - 127,790,792 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379130,548,305 - 130,553,052 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,588,152 - 129,592,184 (+)NCBINCBI36hg18NCBI36
Build 349127,627,890 - 127,631,917NCBI
Celera9101,199,168 - 101,203,915 (+)NCBI
Cytogenetic Map9q34.11NCBI
HuRef9100,164,574 - 100,169,598 (+)NCBIHuRef
CHM1_19130,699,854 - 130,704,602 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CDK9
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346548
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.