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Gene: CDK9 (cyclin dependent kinase 9) Homo sapiens
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Symbol: CDK9
Name: cyclin dependent kinase 9
Description: Exhibits nucleic acid binding activity; protein serine/threonine kinase activity; and transcription coactivator binding activity. Involved in several processes, including negative regulation of cell cycle arrest; positive regulation of histone modification; and regulation of nucleobase-containing compound metabolic process. Localizes to the PML body; cyclin/CDK positive transcription elongation factor complex; and cytoplasmic ribonucleoprotein granule. Biomarker of congestive heart failure.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-2k; CDC2-related kinase; CDC2L4; cell division cycle 2-like protein kinase 4; cell division protein kinase 9; CTK1; cyclin-dependent kinase 9; PITALRE; serine/threonine protein kinase PITALRE; serine/threonine-protein kinase PITALRE; TAK; tat-associated kinase complex catalytic subunit
Orthologs:
Mus musculus (house mouse) : Cdk9 (cyclin-dependent kinase 9 (CDC2-related kinase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdk9 (cyclin-dependent kinase 9)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk9 (cyclin dependent kinase 9)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK9 (cyclin dependent kinase 9)
Canis lupus familiaris (dog) : CDK9 (cyclin dependent kinase 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk9 (cyclin dependent kinase 9)
Sus scrofa (pig) : CDK9 (cyclin dependent kinase 9)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,786,034 - 127,790,792 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379130,548,305 - 130,553,052 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,588,152 - 129,592,184 (+)NCBINCBI36hg18NCBI36
Build 349127,627,890 - 127,631,917NCBI
Celera9101,199,168 - 101,203,915 (+)NCBI
Cytogenetic Map9q34.11NCBI
HuRef9100,164,574 - 100,169,598 (+)NCBIHuRef
CHM1_19130,699,854 - 130,704,602 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDK9
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346548
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.