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Gene: FPGS (folylpolyglutamate synthase) Homo sapiens
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Symbol: FPGS
Name: folylpolyglutamate synthase
Description: Exhibits tetrahydrofolylpolyglutamate synthase activity. Involved in cell population proliferation; glutamate metabolic process; and tetrahydrofolylpolyglutamate biosynthetic process. Localizes to the cytosol and mitochondrion.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: folylpoly-gamma-glutamate synthetase; folylpolyglutamate synthase, mitochondrial; folylpolyglutamate synthetase; tetrahydrofolate synthase; tetrahydrofolylpolyglutamate synthase
Orthologs:
Mus musculus (house mouse) : Fpgs (folylpolyglutamyl synthetase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fpgs (folylpolyglutamate synthase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fpgs (folylpolyglutamate synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : FPGS (folylpolyglutamate synthase)
Canis lupus familiaris (dog) : FPGS (folylpolyglutamate synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fpgs (folylpolyglutamate synthase)
Sus scrofa (pig) : FPGS (folylpolyglutamate synthase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,802,858 - 127,814,520 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379130,565,137 - 130,576,799 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,604,975 - 129,616,377 (+)NCBINCBI36hg18NCBI36
Build 349127,644,728 - 127,655,892NCBI
Celera9101,215,991 - 101,227,396 (+)NCBI
Cytogenetic Map9q34.11NCBI
HuRef9100,181,664 - 100,193,374 (+)NCBIHuRef
CHM1_19130,716,655 - 130,727,890 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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References - curated
References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
 
More on FPGS
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346571
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.