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Gene: ZBTB18 (zinc finger and BTB domain containing 18) Homo sapiens
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Symbol: ZBTB18
Name: zinc finger and BTB domain containing 18
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; sequence-specific double-stranded DNA binding activity; and transcription coactivator activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Localizes to heterochromatin and nuclear speck. Implicated in autosomal dominant non-syndromic intellectual disability 22.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 58 kDa repressor protein; C2H2-171; MRD22; RP58; TAZ-1; transcriptional repressor RP58; translin-associated zinc finger protein 1; zinc finger and BTB domain-containing protein 18; zinc finger protein 238; zinc finger protein C2H2-171; ZNF238
Orthologs:
Mus musculus (house mouse) : Zbtb18 (zinc finger and BTB domain containing 18)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zbtb18 (zinc finger and BTB domain containing 18)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zbtb18 (zinc finger and BTB domain containing 18)
Pan paniscus (bonobo/pygmy chimpanzee) : ZBTB18 (zinc finger and BTB domain containing 18)
Canis lupus familiaris (dog) : ZBTB18 (zinc finger and BTB domain containing 18)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zbtb18 (zinc finger and BTB domain containing 18)
Sus scrofa (pig) : ZBTB18 (zinc finger and BTB domain containing 18)
Chlorocebus sabaeus (African green monkey) : ZBTB18 (zinc finger and BTB domain containing 18)
Heterocephalus glaber (naked mole-rat) : Zbtb18 (zinc finger and BTB domain containing 18)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1244,048,939 - 244,057,476 (+)EnsemblGRCh38hg38GRCh38
GRCh381244,048,939 - 244,057,476 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371244,212,241 - 244,220,778 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361242,281,184 - 242,287,401 (+)NCBINCBI36hg18NCBI36
Build 341240,540,625 - 240,546,817NCBI
Celera1217,504,910 - 217,511,127 (+)NCBI
Cytogenetic Map1q44NCBI
HuRef1214,598,471 - 214,604,688 (+)NCBIHuRef
CHM1_11245,484,555 - 245,493,088 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ZBTB18
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346592
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.