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Gene: GPR50 (G protein-coupled receptor 50) Homo sapiens
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Symbol: GPR50
Name: G protein-coupled receptor 50
Description: This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H9; Mel1c; melatonin-related receptor; MGC125342
Orthologs:
Mus musculus (house mouse) : Gpr50 (G-protein-coupled receptor 50)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gpr50 (G protein-coupled receptor 50)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpr50 (G protein-coupled receptor 50)
Pan paniscus (bonobo/pygmy chimpanzee) : GPR50 (G protein-coupled receptor 50)
Canis lupus familiaris (dog) : GPR50 (G protein-coupled receptor 50)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpr50 (G protein-coupled receptor 50)
Sus scrofa (pig) : GPR50 (G protein-coupled receptor 50)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X151,176,584 - 151,182,855 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X150,345,056 - 150,349,937 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X150,095,717 - 150,100,588 (+)NCBINCBI36hg18NCBI36
Build 34X150,015,692 - 150,020,505NCBI
CeleraX150,593,370 - 150,598,251 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX139,204,459 - 139,209,328 (+)NCBIHuRef
CHM1_1X150,219,098 - 150,223,979 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GPR50
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346636
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.