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Gene: IRX2 (iroquois homeobox 2) Homo sapiens
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Symbol: IRX2
Name: iroquois homeobox 2
Description: Exhibits sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: homeodomain protein IRXA2; iroquois homeobox protein 2; iroquois-class homeodomain protein IRX-2; IRXA2
Orthologs:
Mus musculus (house mouse) : Irx2 (Iroquois homeobox 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Irx2 (iroquois homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irx2 (iroquois homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IRX2 (iroquois homeobox 2)
Canis lupus familiaris (dog) : IRX2 (iroquois homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irx2 (iroquois homeobox 2)
Sus scrofa (pig) : IRX2 (iroquois homeobox 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl52,745,845 - 2,751,677 (-)Ensembl
GRCh3852,707,930 - 2,751,677 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3752,746,279 - 2,751,769 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3652,799,880 - 2,804,769 (-)NCBINCBI36hg18NCBI36
Build 3452,799,879 - 2,804,769NCBI
Celera52,778,127 - 2,783,618 (-)NCBI
Cytogenetic Map5p15.33NCBI
HuRef52,722,301 - 2,727,305 (-)NCBIHuRef
CHM1_152,746,153 - 2,751,637 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on IRX2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346652
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.