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Gene: H2AB1 (H2A.B variant histone 1) Homo sapiens
Symbol: H2AB1
Name: H2A.B variant histone 1
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most centromeric copy which is in intron 22 of the F8 gene. [provided by RefSeq, Oct 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H2A Barr body-deficient; H2A histone family member B1; H2A histone family, member B1; H2A.B; H2A.Bbd; H2AFB1; histone H2A-Bbd type 1
Mus musculus (house mouse) : H2afb1 (H2A histone family member B1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102021406 (histone H2A)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100992822 (histone H2A-Bbd type 2/3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101967165 (histone H2A-Bbd type 2/3)
Sus scrofa (pig) : LOC100517800 (histone H2A-Bbd type 2/3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X154,885,042 - 154,885,558 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X154,113,317 - 154,113,833 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,766,511 - 153,767,027 (+)NCBINCBI36hg18NCBI36
CeleraX154,271,936 - 154,272,452 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,656,817 - 142,657,333 (+)NCBIHuRef
CHM1_1X154,025,079 - 154,025,595 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H2AB1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346656
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.