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Gene: WNK3 (WNK lysine deficient protein kinase 3) Homo sapiens
Symbol: WNK3
Name: WNK lysine deficient protein kinase 3
Description: This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ30437; FLJ42662; KIAA1566; PRKWNK3; protein kinase with no lysine 3; serine/threonine-protein kinase WNK3
Mus musculus (house mouse) : Wnk3 (WNK lysine deficient protein kinase 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wnk3 (WNK lysine deficient protein kinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wnk3 (WNK lysine deficient protein kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : WNK3 (WNK lysine deficient protein kinase 3)
Canis lupus familiaris (dog) : WNK3 (WNK lysine deficient protein kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnk3 (WNK lysine deficient protein kinase 3)
Sus scrofa (pig) : WNK3 (WNK lysine deficient protein kinase 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X54,192,823 - 54,358,695 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X54,219,256 - 54,384,438 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X54,239,580 - 54,401,163 (-)NCBINCBI36hg18NCBI36
Build 34X54,105,875 - 54,267,459NCBI
CeleraX58,050,484 - 58,215,673 (-)NCBI
Cytogenetic MapXp11.22NCBI
HuRefX51,270,978 - 51,435,935 (-)NCBIHuRef
CHM1_1X54,209,950 - 54,375,102 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on WNK3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346670
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.