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Gene: C1QB (complement C1q B chain) Homo sapiens
Symbol: C1QB
Name: complement C1q B chain
Description: Predicted to have protein homodimerization activity. Predicted to be involved in synapse pruning. Localizes to the blood microparticle and collagen-containing extracellular matrix. Biomarker of Alzheimer's disease and ocular hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: complement C1q chain B; complement C1q subcomponent subunit B; complement component 1, q subcomponent, B chain; complement component 1, q subcomponent, beta polypeptide; complement component C1q, B chain; complement subcomponent C1q chain B
Mus musculus (house mouse) : C1qb (complement component 1, q subcomponent, beta polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : C1qb (complement C1q B chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : C1qb (complement C1q B chain)
Pan paniscus (bonobo/pygmy chimpanzee) : C1QB (complement C1q B chain)
Canis lupus familiaris (dog) : C1QB (complement C1q B chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C1qb (complement C1q B chain)
Sus scrofa (pig) : C1QB (complement C1q B chain)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38122,653,236 - 22,661,637 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37122,979,682 - 22,988,130 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,852,269 - 22,860,616 (+)NCBINCBI36hg18NCBI36
Build 34122,731,192 - 22,733,433NCBI
Celera121,304,397 - 21,312,691 (+)NCBI
Cytogenetic Map1p36.12NCBI
HuRef121,224,021 - 21,232,298 (+)NCBIHuRef
CHM1_1123,092,196 - 23,100,535 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on C1QB
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346671
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.