Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TLR9 (toll like receptor 9) Homo sapiens
Analyze
Symbol: TLR9
Name: toll like receptor 9
Description: Exhibits interleukin-1 receptor binding activity and siRNA binding activity. Involved in several processes, including positive regulation of cytokine production; regulation of DNA-binding transcription factor activity; and regulation of signal transduction. Localizes to the apical plasma membrane; basolateral plasma membrane; and cytoplasm. Implicated in several diseases, including allergic bronchopulmonary aspergillosis; cystic fibrosis; glomerulonephritis (multiple); lung disease (multiple); and systemic lupus erythematosus. Biomarker of several diseases, including alcoholic liver cirrhosis; cervix uteri carcinoma in situ; cutaneous leishmaniasis; lung disease (multiple); and nose disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD289; toll-like receptor 9
Orthologs:
Mus musculus (house mouse) : Tlr9 (toll-like receptor 9)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tlr9 (toll-like receptor 9)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlr9 (toll like receptor 9)
Canis lupus familiaris (dog) : TLR9 (toll like receptor 9)
Sus scrofa (pig) : TLR9 (toll like receptor 9)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,221,080 - 52,226,163 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37352,255,096 - 52,260,179 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,230,138 - 52,235,219 (-)NCBINCBI36hg18NCBI36
Build 34352,230,137 - 52,233,247NCBI
Celera352,234,410 - 52,239,491 (-)NCBI
Cytogenetic Map3p21.2NCBI
HuRef352,317,258 - 52,322,341 (-)NCBIHuRef
CHM1_1352,207,624 - 52,212,707 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TLR9
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346715
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.