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Gene: PRICKLE1 (prickle planar cell polarity protein 1) Homo sapiens
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Symbol: PRICKLE1
Name: prickle planar cell polarity protein 1
Description: Predicted to have zinc ion binding activity. Involved in several processes, including negative regulation of cardiac muscle cell myoblast differentiation; positive regulation of cellular protein metabolic process; and protein import into nucleus. Localizes to the cytosol and nuclear membrane. Implicated in progressive myoclonus epilepsy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EPM1B; FLJ31627; FLJ31937; MGC138902; MGC138903; prickle homolog 1; prickle-like 1; prickle-like protein 1; REST (RE-1 silencing transcription factor)/NRSF (neuron-restrictive silencer factor)-interacting LIM domain protein; REST/NRSF-interacting LIM domain protein 1; RILP
Orthologs:
Mus musculus (house mouse) : Prickle1 (prickle planar cell polarity protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prickle1 (prickle planar cell polarity protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prickle1 (prickle planar cell polarity protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PRICKLE1 (prickle planar cell polarity protein 1)
Canis lupus familiaris (dog) : PRICKLE1 (prickle planar cell polarity protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prickle1 (prickle planar cell polarity protein 1)
Sus scrofa (pig) : PRICKLE1 (prickle planar cell polarity protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1242,456,757 - 42,590,355 (-)Ensembl
GRCh381242,456,757 - 42,589,755 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371242,852,140 - 42,983,572 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361241,139,341 - 41,269,745 (-)NCBINCBI36hg18NCBI36
Build 341241,139,340 - 41,269,745NCBI
Celera1241,653,996 - 41,785,497 (-)NCBI
Cytogenetic Map12q12NCBI
HuRef1239,878,936 - 40,010,599 (-)NCBIHuRef
CHM1_11242,818,791 - 42,950,331 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PRICKLE1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346789
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.