Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: AWAT1 (acyl-CoA wax alcohol acyltransferase 1) Homo sapiens
Analyze
Symbol: AWAT1
Name: acyl-CoA wax alcohol acyltransferase 1
Description: The protein encoded by this gene belongs to the diacylglycerol acyltransferase family. It esterifies long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that this enzyme plays a central role in lipid metabolism in skin. Consistent with this observation, this protein is predominantly expressed in the sebaceous gland of the skin. [provided by RefSeq, Sep 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DGA2; DGAT2L3; diacyl-glycerol acyltransferase 2; diacylglycerol acyltransferase 2; diacylglycerol O-acyltransferase 2-like 3; diacylglycerol O-acyltransferase 2-like protein 3; long-chain-alcohol O-fatty-acyltransferase 1
Orthologs:
Mus musculus (house mouse) : Awat1 (acyl-CoA wax alcohol acyltransferase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Awat1 (acyl-CoA wax alcohol acyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Awat1 (acyl-CoA wax alcohol acyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AWAT1 (acyl-CoA wax alcohol acyltransferase 1)
Canis lupus familiaris (dog) : AWAT1 (acyl-CoA wax alcohol acyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Awat1 (acyl-CoA wax alcohol acyltransferase 1)
Sus scrofa (pig) : AWAT1 (acyl-CoA wax alcohol acyltransferase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X70,233,489 - 70,240,661 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X69,454,505 - 69,460,511 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X69,371,271 - 69,376,865 (+)NCBINCBI36hg18NCBI36
CeleraX69,807,845 - 69,813,851 (+)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX63,275,596 - 63,281,709 (+)NCBIHuRef
CHM1_1X69,348,486 - 69,354,491 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
 
More on AWAT1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346796
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.