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Gene: ARHGEF10 (Rho guanine nucleotide exchange factor 10) Homo sapiens
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Symbol: ARHGEF10
Name: Rho guanine nucleotide exchange factor 10
Description: Exhibits Rho guanyl-nucleotide exchange factor activity and kinesin binding activity. Involved in several processes, including activation of GTPase activity; microtubule cytoskeleton organization; and positive regulation of stress fiber assembly. Localizes to centrosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686H0726; GEF10; MGC131664; Rho guanine nucleotide exchange factor (GEF) 10; SNCV
Orthologs:
Mus musculus (house mouse) : Arhgef10 (Rho guanine nucleotide exchange factor (GEF) 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arhgef10 (Rho guanine nucleotide exchange factor 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgef10 (Rho guanine nucleotide exchange factor 10)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGEF10 (Rho guanine nucleotide exchange factor 10)
Canis lupus familiaris (dog) : ARHGEF10 (Rho guanine nucleotide exchange factor 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgef10 (Rho guanine nucleotide exchange factor 10)
Sus scrofa (pig) : ARHGEF10 (Rho guanine nucleotide exchange factor 10)
Chlorocebus sabaeus (African green monkey) : ARHGEF10 (Rho guanine nucleotide exchange factor 10)
Heterocephalus glaber (naked mole-rat) : Arhgef10 (Rho guanine nucleotide exchange factor 10)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl81,823,926 - 1,958,641 (+)EnsemblGRCh38hg38GRCh38
GRCh3881,823,926 - 1,958,641 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3781,772,149 - 1,906,807 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3681,759,556 - 1,894,214 (+)NCBINCBI36hg18NCBI36
Build 3481,808,165 - 1,894,206NCBI
Celera81,715,545 - 1,849,273 (+)NCBI
Cytogenetic Map8p23.3NCBI
HuRef81,586,197 - 1,723,095 (+)NCBIHuRef
CHM1_181,772,104 - 1,906,332 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on ARHGEF10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346816
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.