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Gene: PMPCA (peptidase, mitochondrial processing subunit alpha) Homo sapiens
Symbol: PMPCA
Name: peptidase, mitochondrial processing subunit alpha
Description: Predicted to contribute to endopeptidase activity. Involved in protein processing involved in protein targeting to mitochondrion. Localizes to the mitochondrial inner membrane. Implicated in autosomal recessive spinocerebellar ataxia 2.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Alpha-MPP; cerebellar ataxia 1 (autosomal recessive); Cerebellar ataxia-1; CLA1; CPD3; FLJ26258; inositol polyphosphate-5-phosphatase, 72 kD; INPP5E; KIAA0123; MGC104197; mitochondrial matrix processing protease, alpha subunit; mitochondrial-processing peptidase subunit alpha; P-55; peptidase (mitochondrial processing) alpha; peptidase, mitochondrial processing alpha subunit; SCAR2; spinocerebellar ataxia, autosomal recessive 2
Mus musculus (house mouse) : Pmpca (peptidase (mitochondrial processing) alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pmpca (peptidase, mitochondrial processing subunit alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pmpca (peptidase, mitochondrial processing alpha subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : PMPCA (peptidase, mitochondrial processing alpha subunit)
Canis lupus familiaris (dog) : PMPCA (peptidase, mitochondrial processing alpha subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pmpca (peptidase, mitochondrial processing alpha subunit)
Sus scrofa (pig) : PMPCA (peptidase, mitochondrial processing alpha subunit)
Chlorocebus sabaeus (green monkey) : PMPCA (peptidase, mitochondrial processing subunit alpha)
Heterocephalus glaber (naked mole-rat) : Pmpca (peptidase, mitochondrial processing subunit alpha)
more info ...
Related Pseudogenes: PMPCAP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl9136,410,641 - 136,423,761 (+)Ensembl
GRCh389136,410,573 - 136,423,761 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379139,305,110 - 139,318,213 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,424,937 - 138,438,034 (+)NCBINCBI36hg18NCBI36
Build 349136,580,952 - 136,594,049NCBI
Celera9109,819,961 - 109,833,058 (+)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9108,764,482 - 108,777,579 (+)NCBIHuRef
CHM1_19139,453,229 - 139,466,417 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PMPCA
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346872
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.