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Gene: SLC4A8 (solute carrier family 4 member 8) Homo sapiens
Symbol: SLC4A8
Name: solute carrier family 4 member 8
CRRD ID: 1346907
Description: Exhibits chloride transmembrane transporter activity and sodium:bicarbonate symporter activity. Involved in several processes, including bicarbonate transport; inorganic ion transmembrane transport; and regulation of intracellular pH. Localizes to dendrite.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp761B2318; electroneutral Na(+)-driven Cl-HCO3 exchanger; electroneutral sodium bicarbonate exchanger 1; FLJ46462; k-NBC3; Na+-driven Cl-HCO3 exchanger; NBC3; NDCBE; solute carrier family 4, sodium bicarbonate cotransporter, member 8
Mus musculus (house mouse) : Slc4a8 (solute carrier family 4 (anion exchanger), member 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc4a8 (solute carrier family 4 member 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc4a8 (solute carrier family 4 member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC4A8 (solute carrier family 4 member 8)
Canis lupus familiaris (dog) : SLC4A8 (solute carrier family 4 member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc4a8 (solute carrier family 4 member 8)
Sus scrofa (pig) : SLC4A8 (solute carrier family 4 member 8)
Chlorocebus sabaeus (African green monkey) : SLC4A8 (solute carrier family 4 member 8)
Heterocephalus glaber (naked mole-rat) : Slc4a8 (solute carrier family 4 member 8)
more info ...
Related Pseudogenes: LOC100422524  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1251,391,317 - 51,515,763 (+)EnsemblGRCh38hg38GRCh38
GRCh381251,391,317 - 51,515,763 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371251,785,101 - 51,909,547 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361250,104,861 - 50,189,247 (+)NCBINCBI36hg18NCBI36
Build 341250,105,023 - 50,177,915NCBI
Celera1250,620,062 - 50,705,110 (+)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1248,818,058 - 48,942,408 (+)NCBIHuRef
CHM1_11251,751,635 - 51,876,068 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLC4A8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1346907
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.