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Gene: OPN1MW (opsin 1, medium wave sensitive) Homo sapiens
Symbol: OPN1MW
Name: opsin 1, medium wave sensitive
Description: This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CBBM; CBD; COD5; cone dystrophy 5 (X-linked); GCP; GOP; green cone photoreceptor pigment; green cone pigment; green-sensitive opsin; medium-wave-sensitive opsin 1; MGC176615; MGC177321; MGC198468; MGC198469; OPN1MW1; OPN1MW2; opsin 1 (cone pigments), medium-wave-sensitive; opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan); photopigment apoprotein
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X154,182,596 - 154,196,861 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,448,085 - 153,462,352 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,101,361 - 153,114,725 (+)NCBINCBI36hg18NCBI36
Build 34X153,006,131 - 153,019,496NCBI
CeleraX153,643,424 - 153,658,069 (+)NCBI
Cytogenetic MapXq28NCBI
CHM1_1X153,322,583 - 153,336,848 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on OPN1MW
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347075
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.