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Gene: KMT2C (lysine methyltransferase 2C) Homo sapiens
Symbol: KMT2C
Name: lysine methyltransferase 2C
Description: Exhibits histone methyltransferase activity (H3-K4 specific). Predicted to be involved in positive regulation of transcription by RNA polymerase II. Localizes to the MLL3/4 complex. Implicated in Kleefstra syndrome; esophagus squamous cell carcinoma; and squamous cell carcinoma. Biomarker of prostate cancer and stomach carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ALR-like protein; DKFZp686C08112; FLJ12625; FLJ38309; HALR; histone-lysine N-methyltransferase 2C; histone-lysine N-methyltransferase MLL3; histone-lysine N-methyltransferase, H3 lysine-4 specific; homologous to ALR protein; KIAA1506; KLEFS2; lysine (K)-specific methyltransferase 2C; lysine N-methyltransferase 2C; MGC119851; MGC119852; MGC119853; MLL3; myeloid/lymphoid or mixed-lineage leukemia 3; myeloid/lymphoid or mixed-lineage leukemia protein 3
Mus musculus (house mouse) : Kmt2c (lysine (K)-specific methyltransferase 2C)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kmt2c (lysine methyltransferase 2C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kmt2c (lysine methyltransferase 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : KMT2C (lysine methyltransferase 2C)
Canis lupus familiaris (dog) : KMT2C (lysine methyltransferase 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kmt2c (lysine methyltransferase 2C)
Sus scrofa (pig) : KMT2C (lysine methyltransferase 2C)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh387152,134,925 - 152,436,642 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377151,832,010 - 152,133,090 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367151,462,943 - 151,764,023 (-)NCBINCBI36hg18NCBI36
Build 347151,271,503 - 151,570,699NCBI
Celera7146,389,572 - 146,690,258 (-)NCBI
Cytogenetic Map7q36.1NCBI
HuRef7145,643,457 - 145,868,582 (-)NCBIHuRef
CHM1_17151,840,538 - 152,142,092 (-)NCBICHM1_1
CRA_TCAGchr7v27151,159,181 - 151,460,261 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences