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Gene: MUC5B (mucin 5B, oligomeric mucus/gel-forming) Homo sapiens
Symbol: MUC5B
Name: mucin 5B, oligomeric mucus/gel-forming
Description: Predicted to be involved in O-glycan processing and stimulatory C-type lectin receptor signaling pathway. Localizes to intracellular membrane-bounded organelle. Implicated in bronchiolitis; idiopathic pulmonary fibrosis; and urinary bladder cancer. Biomarker of several diseases, including cholangiocarcinoma; chronic obstructive pulmonary disease; cystic fibrosis; pancreatic ductal carcinoma; and sinusitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cervical mucin MUC5B; high molecular weight mucin; high molecular weight salivary mucin MG1; MG1; MUC-5B; MUC5; MUC9; mucin 5, subtype B, tracheobronchial; mucin, salivary (high molecular weight); mucin-5 subtype B, tracheobronchial; mucin-5B; sublingual gland mucin
Mus musculus (house mouse) : Muc5b (mucin 5, subtype B, tracheobronchial)  MGI  Alliance
Rattus norvegicus (Norway rat) : Muc5b (mucin 5B, oligomeric mucus/gel-forming)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Muc5b (mucin 5B, oligomeric mucus/gel-forming)
Pan paniscus (bonobo/pygmy chimpanzee) : MUC5B (mucin 5B, oligomeric mucus/gel-forming)
Canis lupus familiaris (dog) : MUC5B (mucin 5B, oligomeric mucus/gel-forming)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Muc5b (mucin 5B, oligomeric mucus/gel-forming)
Sus scrofa (pig) : MUC5B (mucin 5B, oligomeric mucus/gel-forming)
Chlorocebus sabaeus (African green monkey) : MUC5B (mucin 5B, oligomeric mucus/gel-forming)
Heterocephalus glaber (naked mole-rat) : Muc5b (mucin 5B, oligomeric mucus/gel-forming)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl111,223,066 - 1,262,172 (+)EnsemblGRCh38hg38GRCh38
GRCh38111,223,066 - 1,262,172 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37111,244,295 - 1,283,406 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,200,872 - 1,239,982 (+)NCBINCBI36hg18NCBI36
Celera111,282,436 - 1,319,815 (+)NCBI
Cytogenetic Map11p15.5NCBI
HuRef111,037,643 - 1,074,965 (+)NCBIHuRef
CHM1_1111,243,203 - 1,282,327 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MUC5B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347084
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-05-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.