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Gene: IKBKG (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma) Homo sapiens
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Symbol: IKBKG
Name: inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
CRRD ID: 1347094
Description: Exhibits several functions, including linear polyubiquitin binding activity; protein dimerization activity; and transferrin receptor binding activity. Involved in several processes, including establishment of vesicle localization; positive regulation of I-kappaB kinase/NF-kappaB signaling; and regulation of transcription, DNA-templated. Localizes to several cellular components, including IkappaB kinase complex; spindle; and ubiquitin ligase complex. Implicated in Behcet's disease; Bloch-Sulzberger syndrome; hypohidrotic ectodermal dysplasia; immunodeficiency 33; and learning disability.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AMCBX1; EDAID1; FIP-3; FIP3; Fip3p; I-kappa-B kinase subunit gamma; IkB kinase gamma subunit; ikB kinase subunit gamma; ikB kinase-associated protein 1; IKK-gamma; IKKAP1; IKKG; IMD33; incontinentia pigmenti; incontinentia pigmenti 1 (sporadic, associated with X chromosome rearrangements); incontinentia pigmenti 2 (familial, male-lethal type); inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of nuclear factor kappa B kinase subunit gamma; inhibitor of nuclear factor kappa-B kinase subunit gamma; IP; IP1; IP2; IPD2; NEMO; NF-kappa-B essential modifier; NF-kappa-B essential modulator; NFkappaB essential modulator; ZC2HC9
Orthologs:
Related Pseudogenes: IKBKGP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX154,541,199 - 154,565,046 (+)EnsemblGRCh38hg38GRCh38
GRCh38X154,541,238 - 154,565,046 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,769,419 - 153,796,804 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,423,653 - 153,446,455 (+)NCBINCBI36hg18NCBI36
Build 34X153,339,765 - 153,356,964NCBI
CeleraX153,931,508 - 153,953,200 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,346,885 - 142,356,952 (+)NCBIHuRef
CHM1_1X153,682,224 - 153,705,030 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

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Nomenclature History
 
More on IKBKG
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347094
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.