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Gene: MED25 (mediator complex subunit 25) Homo sapiens
Symbol: MED25
Name: mediator complex subunit 25
Description: Exhibits retinoid X receptor binding activity and transcription coactivator binding activity. Involved in several processes, including positive regulation of chromatin binding activity; positive regulation of mediator complex assembly; and regulation of transcription by RNA polymerase II. Localizes to nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACID1; activator interaction domain-containing protein 1; activator-recruited cofactor 92 kDa component; ARC/mediator transcriptional coactivator subunit; ARC92; BVSYS; CMT2B2; DKFZp434K0512; mediator of RNA polymerase II transcription subunit 25; mediator of RNA polymerase II transcription, subunit 25 homolog; MGC70671; P78; prostate-derived protein 78 kDa; PTOV2; TCBAP0758
Mus musculus (house mouse) : Med25 (mediator complex subunit 25)  MGI  Alliance
Rattus norvegicus (Norway rat) : Med25 (mediator complex subunit 25)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Med25 (mediator complex subunit 25)
Pan paniscus (bonobo/pygmy chimpanzee) : MED25 (mediator complex subunit 25)
Canis lupus familiaris (dog) : MED25 (mediator complex subunit 25)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Med25 (mediator complex subunit 25)
Sus scrofa (pig) : MED25 (mediator complex subunit 25)
Chlorocebus sabaeus (African green monkey) : MED25 (mediator complex subunit 25)
Heterocephalus glaber (naked mole-rat) : Med25 (mediator complex subunit 25)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1949,818,279 - 49,840,383 (+)EnsemblGRCh38hg38GRCh38
GRCh381949,818,289 - 49,840,384 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371950,321,319 - 50,340,237 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,013,358 - 55,032,049 (+)NCBINCBI36hg18NCBI36
Build 341955,013,357 - 55,032,049NCBI
Celera1947,190,990 - 47,209,687 (+)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1946,697,846 - 46,716,581 (+)NCBIHuRef
CHM1_11950,323,376 - 50,342,077 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MED25
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347126
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.