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Gene: IFNL1 (interferon lambda 1) Homo sapiens
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Symbol: IFNL1
Name: interferon lambda 1
CRRD ID: 1347142
Description: Exhibits interleukin-28 receptor binding activity. Involved in several processes, including negative regulation of immune response; positive regulation of macromolecule metabolic process; and regulation of gene expression. Localizes to extracellular region and interleukin-28 receptor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cytokine Zcyto21; IFN-lambda-1; IL-29; IL29; interferon lambda-1; interferon, lambda 1; interferon-lambda-1; interleukin 29 (interferon, lambda 1); interleukin-29
Orthologs:
Rattus norvegicus (Norway rat) : Ifnl1 (interferon, lambda 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100976419 (interferon lambda-1)
Canis lupus familiaris (dog) : IL29L (interleukin 29-like)
Sus scrofa (pig) : IL29 (interleukin 29 (interferon, lambda 1))
Chlorocebus sabaeus (African green monkey) : IFNL1 (interferon lambda 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1939,296,407 - 39,298,673 (+)EnsemblGRCh38hg38GRCh38
GRCh381939,296,407 - 39,298,673 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371939,786,965 - 39,789,312 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361944,478,805 - 44,481,152 (+)NCBINCBI36hg18NCBI36
Build 341944,478,804 - 44,481,152NCBI
Celera1936,588,638 - 36,590,984 (+)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1936,233,484 - 36,235,831 (+)NCBIHuRef
CHM1_11939,787,771 - 39,790,118 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IFNL1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347142
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.