Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: REPS2 (RALBP1 associated Eps domain containing 2) Homo sapiens
Analyze
Symbol: REPS2
Name: RALBP1 associated Eps domain containing 2
Description: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: partner of Ral-binding protein 1; partner of RalBP1; POB1; ralBP1-associated Eps domain-containing protein 2; RALBP1-interacting protein 2
Orthologs:
Mus musculus (house mouse) : Reps2 (RALBP1 associated Eps domain containing protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Reps2 (RALBP1 associated Eps domain containing 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Reps2 (RALBP1 associated Eps domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : REPS2 (RALBP1 associated Eps domain containing 2)
Canis lupus familiaris (dog) : REPS2 (RALBP1 associated Eps domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Reps2 (RALBP1 associated Eps domain containing 2)
Sus scrofa (pig) : REPS2 (RALBP1 associated Eps domain containing 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X16,946,691 - 17,220,724 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X16,964,814 - 17,171,403 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X16,874,735 - 17,081,324 (+)NCBINCBI36hg18NCBI36
Build 34X16,724,470 - 16,925,392NCBI
CeleraX21,145,068 - 21,292,536 (+)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX14,724,183 - 14,930,872 (+)NCBIHuRef
CHM1_1X16,995,199 - 17,202,074 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on REPS2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347143
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.