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Gene: USP11 (ubiquitin specific peptidase 11) Homo sapiens
Symbol: USP11
Name: ubiquitin specific peptidase 11
Description: Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: deubiquitinating enzyme 11; ubiquitin carboxyl-terminal hydrolase 11; ubiquitin carboxyl-terminal hydrolase, X-linked; ubiquitin specific protease 11; ubiquitin thioesterase 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; ubiquitin-specific-processing protease 11; UHX1
Mus musculus (house mouse) : Usp11 (ubiquitin specific peptidase 11)  MGI  Alliance
Rattus norvegicus (Norway rat) : Usp11 (ubiquitin specific peptidase 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Usp11 (ubiquitin specific peptidase 11)
Pan paniscus (bonobo/pygmy chimpanzee) : USP11 (ubiquitin specific peptidase 11)
Canis lupus familiaris (dog) : USP11 (ubiquitin specific peptidase 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Usp11 (ubiquitin specific peptidase 11)
Sus scrofa (pig) : USP11 (ubiquitin specific peptidase 11)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X47,232,915 - 47,248,328 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X47,092,089 - 47,107,727 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X46,977,258 - 46,992,671 (+)NCBINCBI36hg18NCBI36
Build 34X46,848,567 - 46,863,981NCBI
CeleraX51,287,607 - 51,302,967 (+)NCBI
Cytogenetic MapXp11.3NCBI
HuRefX44,802,084 - 44,817,144 (+)NCBIHuRef
CHM1_1X47,123,812 - 47,139,152 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on USP11
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347156
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.