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Gene: ZIC3 (Zic family member 3) Homo sapiens
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Symbol: ZIC3
Name: Zic family member 3
Description: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: heterotaxy 1; HTX; HTX1; VACTERLX; Zic family member 3 (odd-paired homolog, Drosophila); zinc finger protein 203; zinc finger protein of the cerebellum 3; zinc finger protein ZIC 3; ZNF203
Orthologs:
Mus musculus (house mouse) : Zic3 (zinc finger protein of the cerebellum 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zic3 (Zic family member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zic3 (Zic family member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ZIC3 (Zic family member 3)
Canis lupus familiaris (dog) : ZIC3 (Zic family member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zic3 (Zic family member 3)
Sus scrofa (pig) : ZIC3 (Zic family member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X137,566,127 - 137,577,691 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X136,648,346 - 136,654,259 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X136,476,012 - 136,481,925 (+)NCBINCBI36hg18NCBI36
Build 34X136,373,865 - 136,379,777NCBI
CeleraX137,014,356 - 137,020,269 (+)NCBI
Cytogenetic MapXq26.3NCBI
HuRefX125,916,990 - 125,922,902 (+)NCBIHuRef
CHM1_1X136,559,744 - 136,565,657 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ZIC3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347201
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-17
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.