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Gene: LINC00312 (long intergenic non-protein coding RNA 312) Homo sapiens
Symbol: LINC00312
Name: long intergenic non-protein coding RNA 312
Description: This gene produces an intronless transcript that is thought to function as a tumor suppressor. This transcript is downregulated in nasopharyngeal carcinoma and is a negative regulator of estrogen receptor signaling. A common polymorphism in this transcript allows the production of a 94 aa open reading frame in some individuals, which may interact directly with estrogen receptor 1 (PMID:15474036). This open reading frame does not exist on the reference genome haplotype, which is hypothesized to function through a non-coding RNA product. [provided by RefSeq, Mar 2017]
Type: ncrna
RefSeq Status: REVIEWED
Also known as: ERR-10; ERR10; LMCD1DN; LOH3CR2A; NAG-7; NAG7; NCRNA00312
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3838,571,782 - 8,574,668 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3738,613,468 - 8,616,354 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3638,588,891 - 8,590,576 (+)NCBINCBI36hg18NCBI36
Build 3438,588,890 - 8,590,562NCBI
Celera38,550,226 - 8,552,338 (+)NCBI
Cytogenetic Map3p25.3NCBI
HuRef38,548,503 - 8,551,388 (+)NCBIHuRef
CHM1_138,564,118 - 8,567,004 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
References - curated
References - uncurated


Position Markers
miRNA Target Status



Nucleotide Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LINC00312
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347210
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.