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Gene: CCR4 (C-C motif chemokine receptor 4) Homo sapiens
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Symbol: CCR4
Name: C-C motif chemokine receptor 4
Description: Predicted to have C-C chemokine binding activity and C-C chemokine receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Localizes to the plasma membrane. Biomarker of osteoarthritis; pancreatic cancer; and rheumatoid arthritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-C chemokine receptor type 4; C-C CKR-4; CC-CKR-4; CCR-4; CD194; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4; ChemR13; CKR4; CMKBR4; HGCN:14099; K5-5; MGC88293
Orthologs:
Mus musculus (house mouse) : Ccr4 (chemokine (C-C motif) receptor 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccr4 (C-C motif chemokine receptor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccr4 (C-C motif chemokine receptor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : CCR4 (C-C motif chemokine receptor 4)
Canis lupus familiaris (dog) : CCR4 (C-C motif chemokine receptor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccr4 (C-C motif chemokine receptor 4)
Sus scrofa (pig) : CCR4 (C-C motif chemokine receptor 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38332,951,555 - 32,956,349 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37332,993,066 - 32,996,403 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36332,968,070 - 32,971,407 (+)NCBINCBI36hg18NCBI36
Build 34332,968,069 - 32,971,407NCBI
Celera332,935,667 - 32,939,047 (+)NCBI
Cytogenetic Map3p22.3NCBI
HuRef332,932,639 - 32,935,976 (+)NCBIHuRef
CHM1_1332,943,070 - 32,946,407 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CCR4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347259
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.