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Gene: UBR1 (ubiquitin protein ligase E3 component n-recognin 1) Homo sapiens
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Symbol: UBR1
Name: ubiquitin protein ligase E3 component n-recognin 1
Description: Exhibits leucine binding activity. Involved in cellular response to leucine and negative regulation of TOR signaling. Predicted to localize to the cytoplasm and ubiquitin ligase complex. Implicated in Johanson-Blizzard syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E3 ubiquitin-protein ligase UBR1; E3a ligase; Jacobsen syndrome; JBS; MGC142065; MGC142067; N-recognin-1; RING-type E3 ubiquitin transferase UBR1; ubiquitin ligase E3 alpha-I; ubiquitin-protein ligase E3-alpha; ubiquitin-protein ligase E3-alpha-1; ubiquitin-protein ligase E3-alpha-I
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381542,942,897 - 43,106,038 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371543,235,095 - 43,398,286 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361541,022,387 - 41,185,578 (-)NCBINCBI36hg18NCBI36
Build 341541,024,818 - 41,185,512NCBI
Celera1520,005,916 - 20,169,100 (-)NCBI
Cytogenetic Map15q15.2NCBI
HuRef1520,083,513 - 20,246,655 (-)NCBIHuRef
CHM1_11543,353,443 - 43,517,124 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on UBR1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347280
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.