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Gene: GPC4 (glypican 4) Homo sapiens
Symbol: GPC4
Name: glypican 4
Description: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dJ900E8.1 (glypican 4); glypican proteoglycan 4; glypican-4; K-glypican; KPTS
Mus musculus (house mouse) : Gpc4 (glypican 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gpc4 (glypican 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpc4 (glypican 4)
Pan paniscus (bonobo/pygmy chimpanzee) : GPC4 (glypican 4)
Canis lupus familiaris (dog) : GPC4 (glypican 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpc4 (glypican 4)
Sus scrofa (pig) : GPC4 (glypican 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X133,301,036 - 133,415,177 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X132,433,815 - 132,549,205 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X132,262,730 - 132,376,871 (-)NCBINCBI36hg18NCBI36
Build 34X132,160,583 - 132,274,725NCBI
CeleraX132,821,529 - 132,935,634 (-)NCBI
Cytogenetic MapXq26.2NCBI
HuRefX121,838,234 - 121,950,367 (-)NCBIHuRef
CHM1_1X132,346,513 - 132,460,631 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GPC4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347282
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.