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Gene: ADAM28 (ADAM metallopeptidase domain 28) Homo sapiens
Symbol: ADAM28
Name: ADAM metallopeptidase domain 28
Description: Exhibits metallopeptidase activity. Predicted to be involved in spermatogenesis. Localizes to mitochondrion and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: a disintegrin and metalloproteinase domain 28; ADAM 28; ADAM23; disintegrin and metalloproteinase domain-containing protein 28; eMDC II; eMDCII; epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; MDC-L; MDC-Lm; MDC-Ls; MDCL; metalloproteinase-like, disintegrin-like, and cysteine-rich protein L; metalloproteinase-like, disintegrin-like, and cysteine-rich protein-L
Mus musculus (house mouse) : Adam28 (a disintegrin and metallopeptidase domain 28)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adam28 (ADAM metallopeptidase domain 28)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adam28 (ADAM metallopeptidase domain 28)
Pan paniscus (bonobo/pygmy chimpanzee) : ADAM28 (ADAM metallopeptidase domain 28)
Canis lupus familiaris (dog) : ADAM28 (ADAM metallopeptidase domain 28)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adam28 (ADAM metallopeptidase domain 28)
Sus scrofa (pig) : ADAM28 (ADAM metallopeptidase domain 28)
Chlorocebus sabaeus (African green monkey) : ADAM28 (ADAM metallopeptidase domain 28)
Heterocephalus glaber (naked mole-rat) : Adam28 (ADAM metallopeptidase domain 28)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl824,294,069 - 24,359,014 (+)EnsemblGRCh38hg38GRCh38
GRCh38824,294,040 - 24,359,014 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37824,151,553 - 24,212,726 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36824,207,525 - 24,268,671 (+)NCBINCBI36hg18NCBI36
Celera823,115,137 - 23,176,304 (+)NCBI
Cytogenetic Map8p21.2NCBI
HuRef822,696,187 - 22,757,353 (+)NCBIHuRef
CHM1_1824,353,720 - 24,418,703 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ADAM28
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347348
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.