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Gene: LCLAT1 (lysocardiolipin acyltransferase 1) Homo sapiens
Symbol: LCLAT1
Name: lysocardiolipin acyltransferase 1
Description: Exhibits 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phosphatidylinositol acyl-chain remodeling. Localizes to the cytosol and endoplasmic reticulum; PARTICIPATES IN glycerophospholipid metabolic pathway; INTERACTS WITH aflatoxin B1; benzo[a]pyrene; benzo[a]pyrene diol epoxide I.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-acylglycerol-3-phosphate O-acyltransferase 8; 1-AGP acyltransferase 8; 1-AGPAT 8; 1AGPAT8; acyl-CoA:lysocardiolipin acyltransferase 1; AGPAT8; ALCAT1; FLJ37965; HSRG1849; LYCAT; UNQ1849
Mus musculus (house mouse) : Lclat1 (lysocardiolipin acyltransferase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lclat1 (lysocardiolipin acyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lclat1 (lysocardiolipin acyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LCLAT1 (lysocardiolipin acyltransferase 1)
Canis lupus familiaris (dog) : LCLAT1 (lysocardiolipin acyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lclat1 (lysocardiolipin acyltransferase 1)
Sus scrofa (pig) : LCLAT1 (lysocardiolipin acyltransferase 1)
Chlorocebus sabaeus (green monkey) : LCLAT1 (lysocardiolipin acyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Lclat1 (lysocardiolipin acyltransferase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl230,447,226 - 30,644,225 (+)Ensembl
GRCh38230,447,241 - 30,644,225 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37230,670,102 - 30,867,091 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36230,523,627 - 30,720,595 (+)NCBINCBI36hg18NCBI36
Build 34230,581,773 - 30,778,741NCBI
Celera230,513,207 - 30,710,198 (+)NCBI
Cytogenetic Map2p23.1NCBI
HuRef230,408,128 - 30,605,091 (+)NCBIHuRef
CHM1_1230,600,354 - 30,797,383 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on LCLAT1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347425
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.