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Gene: WDR13 (WD repeat domain 13) Homo sapiens
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Symbol: WDR13
Name: WD repeat domain 13
Description: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. A similar protein in mouse is thought to be a negative regulator of the pancreatic beta cell proliferation. Mice lacking this gene exhibit increased pancreatic islet mass and higher serum insulin levels, and are mildly obese. [provided by RefSeq, Nov 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp779C2057; FLJ20563; MG21; WD repeat-containing protein 13
Orthologs:
Mus musculus (house mouse) : Wdr13 (WD repeat domain 13)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wdr13 (WD repeat domain 13)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wdr13 (WD repeat domain 13)
Pan paniscus (bonobo/pygmy chimpanzee) : WDR13 (WD repeat domain 13)
Canis lupus familiaris (dog) : WDR13 (WD repeat domain 13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wdr13 (WD repeat domain 13)
Sus scrofa (pig) : WDR13 (WD repeat domain 13)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X48,590,053 - 48,608,869 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X48,455,880 - 48,463,582 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,340,845 - 48,348,518 (+)NCBINCBI36hg18NCBI36
Build 34X48,212,154 - 48,219,828NCBI
CeleraX53,202,158 - 53,209,859 (-)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,119,373 - 46,127,116 (+)NCBIHuRef
CHM1_1X48,487,115 - 48,494,815 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on WDR13
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347566
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.