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Gene: CD33 (CD33 molecule) Homo sapiens
Symbol: CD33
Name: CD33 molecule
Description: Exhibits protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Localizes to several cellular components, including the Golgi apparatus; external side of plasma membrane; and peroxisome; INTERACTS WITH aflatoxin B1; all-trans-retinoic acid; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD33 antigen (gp67); CD33 molecule transcript; FLJ00391; gp67; myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC-3; SIGLEC3
Mus musculus (house mouse) : Cd33 (CD33 antigen)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd33 (CD33 molecule)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CD33 (CD33 molecule)
Canis lupus familiaris (dog) : LOC100686511 (myeloid cell surface antigen CD33)
Sus scrofa (pig) : LOC110261034 (myeloid cell surface antigen CD33-like)
Chlorocebus sabaeus (African green monkey) : CD33 (CD33 molecule)
more info ...
Related Pseudogenes: SIGLEC17P   SIGLEC21P   SIGLEC22P   SIGLEC29P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1951,225,064 - 51,243,860 (+)EnsemblGRCh38hg38GRCh38
GRCh381951,211,054 - 51,240,016 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371951,728,335 - 51,743,274 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361956,420,147 - 56,435,086 (+)NCBINCBI36hg18NCBI36
Build 341956,420,174 - 56,435,084NCBI
Celera1948,780,420 - 48,795,363 (+)NCBI
Cytogenetic Map19q13.41NCBI
HuRef1948,061,383 - 48,076,328 (+)NCBIHuRef
CHM1_11951,730,399 - 51,745,342 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Cell Lines
Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CD33
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347694
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.